2001
DOI: 10.1001/archpedi.155.5.607
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Abstract: A 15-MONTH-OLD boy had a history of unexplained bleeding from his gums for several weeks and fever for 2 days. He had been fed only cow's milk and oatmeal since age 4 months. On physical examination he had almost no spontaneous movement. His legs were held in a "frog leg" position (Figure 1), were swollen along the long bones, and were tender to palpation. His skin was dry and pale. Hemorrhages of the gingiva were obvious as were 2 blood-filled cysts of the lower ca-nine teeth (Figure 2). The tympanic membrane… Show more

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Cited by 22 publications

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“…Pseudoparalysis may become apparent due to bone pain. 5 The dominant features of this patient were joint pain and inability to walk without visible joint swelling.…”
Section: Before Discussionmentioning
confidence: 80%
“…Scurvy being a rare disorder usually missed by physician leading to a delayed diagnosis. 4,5 Initial manifestations of scurvy are vague like irritability, lack of appetite. 5 As it progresses, there will be generalized tenderness especially over long bones due to subperiosteal hemorrhage.…”
Section: Before Discussionmentioning
confidence: 99%
“…4,5 Initial manifestations of scurvy are vague like irritability, lack of appetite. 5 As it progresses, there will be generalized tenderness especially over long bones due to subperiosteal hemorrhage. Pseudoparalysis may become apparent due to bone pain.…”
Section: Before Discussionmentioning
confidence: 99%
See 2 more Smart Citations
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…Pseudoparalysis may become apparent due to bone pain. 5 The dominant features of this patient were joint pain and inability to walk without visible joint swelling.…”
Section: Before Discussionmentioning
confidence: 80%
“…Scurvy being a rare disorder usually missed by physician leading to a delayed diagnosis. 4,5 Initial manifestations of scurvy are vague like irritability, lack of appetite. 5 As it progresses, there will be generalized tenderness especially over long bones due to subperiosteal hemorrhage.…”
Section: Before Discussionmentioning
confidence: 99%
“…4,5 Initial manifestations of scurvy are vague like irritability, lack of appetite. 5 As it progresses, there will be generalized tenderness especially over long bones due to subperiosteal hemorrhage. Pseudoparalysis may become apparent due to bone pain.…”
Section: Before Discussionmentioning
confidence: 99%
See 1 more Smart Citation
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…Swelling may be noted along the shafts of long bones. Pseudoparalysis may be apparent as a result of the bone pain [6]. The dominant symptoms in our patient were joint swelling and pain.…”
Section: Discussionmentioning
confidence: 85%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…This feature has been clinically observed following the reintroduction of vitamin C and resumption of osteoid formation (Noordin et al, 2012; Riepe et al, 2001). …”
Section: Macroscopic Osseous Lesions Of Adult and Juvenile Scurvy: Anmentioning
confidence: 80%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.