Phytochemical Screening of Fish Poison Tree, Barringtonia Asiatica Seed for Potential Biopesticidal Activity and Pharmaceutical Uses

Abstract

The leaves are locally used as vegetable food, herb, spice, and medication for backaches, sore joints, rheumatism, hernia, and diarrhea (Barwick, 2004). According to Stuart (2018), in the Philippines, leaves are heated and applied as topical remedy for stomachache. Similarly, Ravikumar et al. (2015) reported that the Nicobari tribe of India utilized leaves for the treatment of fractures, wounds, de-worming, and pain relief. The flowers are large pinkish-white, which give off a sickly-sweet smell to attract bats and moths, which pollinate them in return.

Barringtonia asiatica Seed Extract Induces G1 Cell Cycle Arrest in Saccharomyces cerevisiae and Exhibits Cytotoxicity in A2780 Human Ovarian Cancer Cells

“…The presence of numerous secondary metabolites found in B. asiatica, such as alkaloids, flavonoids, and glycosides, among others, have been previously reported in seed extracts. The efficacy of saponins, also present in the seed, against cancer cells has been attributed to their ability to inhibit cell proliferation, stimulate apoptosis, and reduce angiogenesis [64]. Therefore, these compounds plausibly account for the cytotoxic activity of B. asiatica seed extract against ovarian carcinoma (A2780) cell line in this study.…”

Secondary Metabolites Identification and Antioxidant Activity Determination of Crude Extract of Barringtonia asiatica l. (kurz) Leaves

“…These compounds, in particular polyphenol, give the antioxidant property. Another reported that the seed of Barringtonia asiatica L. (Kurz) generally has a higher diversity of secondary metabolites such as saponin, terpenoid, tannin, flavonoid, coumarine, cardiac glycoside and alkaloid [12]. Although the study of phytochemical analysis of Barringtonia asiatica L. (Kurz) is already established quiet well, but the same study from different geographical area is important to elucidate its potential locally.…”