Phytochemical Investigation of Schleichera oleosa (Lour.) Oken Leaf

Anjum, Noushin; Hossain, Md. Jamal; Haque, Mohammad Rashedul; Chowdhury, A. K.; Rashid, Mohammad A.; Kuddus, Ruhul

doi:10.3329/bpj.v24i1.51633

Cited by 12 publications

(9 citation statements)

References 14 publications

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“…The whole mixtures were then filtered through a fresh cotton plug and finally with a Whatman No.1 filter paper. The volume of the filtrate was then allowed to evaporate at ambient temperature until approximately 70% solvent was evaporated (Khatun et al, 2021;Anjum et al, 2021).…”

Section: Collection Of Plant Materials and Preparation Of Crude Extractmentioning

confidence: 99%

Stixis suaveolens (Roxb.) Fruit Extract Deciphered Antidepressant and Antidiarrheal Effects via In vivo Approach

et al. 2023

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Depression is a pervasive psychiatric disorder worldwide and diarrhea is considered a leading cause of preventable death for infants and children in developing countries. The current study was done to assess in vivo activities of crude methanol extract of Stixis suaveolens fruit, focusing on antidepressant and antidiarrheal effects. The effect on central nervous system (CNS) was examined by recording the onset of sleep and total sleeping time. Besides, castor oil-induced diarrhea in the mice model was followed while evaluating the antidiarrheal effects. Significant (p<0.01) reduction in onset time (64.8 min) as well as in total sleeping time (64.8 min) were recorded between the test groups and the control. The extract, when given orally, also resulted in a significant (p < 0.001) reduction of diarrheal feces induced by castor oil by 71.43%. The in vivo bioassays demonstrated that the crude methanol extract of the fruit of S. suaveolens contains significant antidiarrheal and CNS stimulating actions. However, further vigorous studies are recommended to isolate and characterize the major phytoconstituents from the plant in order to develop the exact mechanism of actions of the plant against various disorders. Bangladesh Pharmaceutical Journal 26(1): 28-35, 2023 (January)

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Section: Collection Of Plant Materials and Preparation Of Crude Extractmentioning

confidence: 99%

Stixis suaveolens (Roxb.) Fruit Extract Deciphered Antidepressant and Antidiarrheal Effects via In vivo Approach

et al. 2023

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“…On the rooftop garden and indoor garden, many kinds of herbs, shrubs, and trees are cultivated. Bangladesh has a record of more than five hundred various species of medicinal plants (Anjum et al, 2021). Gynura procumbens is also a medicinal plant used for gardening on the rooftop and indoor spaces and have popularity as a diabetic plant in Bangladesh.…”

Section: Introductionmentioning

confidence: 99%

Effect of Organic Amendments and Shade Levels on Growth Performances of Diabetic Plant (Gynura procumbens)

Robi¹,

Prova²,

Das³

et al. 2023

J. Agrofor. Environ.

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The diabetic plant (Gynura procumbens) also recognized as a diabetic plant, contains many medicinal values but is rarely available in local markets and near at hand. Indoor gardening can help in getting the plant within reach easily. The research was conducted to investigate the growth performance of G. procumbens under various organic amendments and shade levels. The experiment was consisted of two factors: different organic amendments and shade levels. Under the first factor, three organic amendments, namely O1= Cow dung, O2= vermicompost, and O3= Trichocompost were included and under the second factor, two shade levelsviz. S1= Full shade (4×100 lux) and S2= Semi-shade (125×100 lux) were imposed. The experiment was designed in a factorial Randomized Complete Block Design (RCBD) with three replications. Plant height (cm), number of leaves, and number of stems per plant were measured and statistically analyzed at 50, 80, and 110 days after transplanting. Means were compared with the DMRT values. Results revealed that, the treatment combination of trichocompost and semi-shade (O3S2) showed highly significant maximum number of leaves (159.33) and stems (18.67) at 110 DAT (p ≤ 0.01). Trichocompost (O3) under semi-shade (S2) condition performed as the best practice for G. procumbens plant growth. Therefore, application of trichocompost under semi-shade conditions could be recommended for Gynura procumbens cultivation.

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“…Since ancient times, people have been exploring nature and searching for new therapeutic agents. This effort led to the discovery of many medicinal plants with healing action to treat various illnesses [4][5][6]. Nearly 80% of the population in the world depends on plant-based medicines as a significant source of healthcare [7][8][9].…”

Section: Introductionmentioning

confidence: 99%

Chemical and Pharmacological Profiling of Wrightia coccinea (Roxb. Ex Hornem.) Sims Focusing Antioxidant, Cytotoxic, Antidiarrheal, Hypoglycemic, and Analgesic Properties

et al. 2022

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The aim of the study was to conduct phytochemical and pharmacological investigations of Wrightia coccinea (Roxb. ex Hornem.) Sims via several in vitro, in vivo, and in silico models. A total of four compounds were identified and isolated from the methanol extract of the bark and the methanol extract of the seed pulp of W. coccinea through successive chromatographic techniques and were characterized as 3β-acetyloxy-olean-12-en-28-ol (1), wrightiadione (2), 22β-hydroxylupeol (3), and β-sitosterol (4) by spectroscopic analysis. The aqueous fraction of the bark and chloroform fraction of the fruits provided the most potent antioxidant capacity (IC50 = 7.22 and 4.5 µg/mL, respectively) in DPPH free radical scavenging assay compared with the standard ascorbic acid (IC50 = 17.45 µg/mL). The methanol bark extract and the methanol fruit coat extract exerted anti-diarrheal activity by inhibiting 74.55 ± 0.67% and 77.78 ± 1.5% (mean ± SEM) of the diarrheal episode in mice, respectively, after four hours of loading the samples. In the hypoglycemic test, the methanol bark extract and the methanol fruit coat extract (400 mg/kg) produced a significant (p < 0.05) reduction in the blood glucose level in mice. Both doses of the plant extracts (200 mg/kg and 400 mg/kg) used in the study induced a significant (p < 0.05) increase in pain reaction time. The in vitro and in vivo findings were supported by the computational studies. The isolated compounds exhibited higher binding affinity compared with the standard drugs towards the active binding sites of glutathione reductase, epidermal growth factor receptor (EGFR), kappa opioid receptor, glucose transporter 3 (GLUT 3), Mu opioid receptor, and cyclooxygenase 2 (COX-2) proteins due to their potent antioxidant, cytotoxic, anti-diarrheal, hypoglycemic, and central and peripheral analgesic properties, respectively. The current findings concluded that W. coccinea might be a potential natural source for managing oxidative stress, diarrhea, hyperglycemia, and pain. Further studies are warranted for extensively phytochemical screening and establishing exact mechanisms of action.

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Phytochemical Investigation of Schleichera oleosa (Lour.) Oken Leaf

Cited by 12 publications

References 14 publications

Stixis suaveolens (Roxb.) Fruit Extract Deciphered Antidepressant and Antidiarrheal Effects via In vivo Approach

Stixis suaveolens (Roxb.) Fruit Extract Deciphered Antidepressant and Antidiarrheal Effects via In vivo Approach

Effect of Organic Amendments and Shade Levels on Growth Performances of Diabetic Plant (Gynura procumbens)

Chemical and Pharmacological Profiling of Wrightia coccinea (Roxb. Ex Hornem.) Sims Focusing Antioxidant, Cytotoxic, Antidiarrheal, Hypoglycemic, and Analgesic Properties

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