Phytochemical analysis and antimicrobial and antioxidant activities of Celosia argentea leaves

Abstract

This study performed the phytochemical screening and bioactivity of Celosia argentea leaves. The phytochemical profile of hexane (Hex), ethyl acetate (AcOEt) and methanolic (MeOH) extracts of C. argentea leaves was observed by Thin Layer Chromatography and spectrophotometric analysis. In the susceptibility test, the disk-diffusion technique was performed. Minimum Inhibitory Concentration (MIC) was assessed by microdilution. Minimum Microbic Concentration (MMC) was determined in the extracts which presented MIC. Antioxidant activities were measured using 2,2-diphenyl-1-picril-hidrazil (DPPH), determination of reducing power and total antioxidant capacity (TAC). The results showed a higher content of phenolic compounds (252.02 ± 0.02 mg GAE/g) in the extract AcOEt, and of tannins (103.72 ± 0.004 mg/EAT/g) in MeOH; this was effective against Micrococcus luteus (inhibition of 24.7 ± 0.6 mm). MIC and CMM of the AcOEt for M. luteus were 0.06 and 0.25 mg/mL, respectively. The MeOH extract eliminated 70.4 ± 0.03% of DPPH radical, whereas AcOEt had greater reducing power (289.23 ± 0.05 mg AA/g) and TAC at a concentration of 250 µg/mL (89.6%). This study revealed that C. argentea has phytochemicals with bactericidal and fungicidal potential, in addition to elevated antioxidant power. Key words: antimicrobial, antioxidant, bioactivity.

Biogenic Zinc oxide nanoparticles from Celosia argentea: toward improved antioxidant, antibacterial, and anticancer activities

“…Similar activity had been reported for green synthesized ZnO NPs from different plants (Table 4). Moreover, the inhibition zone of C. argentea extract against the four bacterial strains was significantly larger than that of Gentamycin, which was due to the presence of bioactive compounds such as alkaloids, flavonoids, phenols, terpenoids, starch, and cellulose (Malomo et al, 2011;Santana et al, 2021).…”

“…Several ailments, including jaundice, inflammation, wound healing, eye diseases, and glandular swellings, had long been treated with C. argentea in traditional medicine. Numerous studies on C. argentea anticancer and antibacterial mechanism have shown evidence that it causes cells to commit suicide through apoptosis (Rub et al, 2015;Rub et al, 2016;Santana et al, 2021). Moreover, C. argentea is a powerful scavenging activity of free radicals.…”

Investigation of phytochemical composition and bioactivity evaluation of extracts from Myrsine umbellata Mart.

“…The phytochemical tests of the different plant extracts of M. umbellata were performed according to the methodology described by (Matos, 1997;Silva Neto et al, 2021), with modifications. These tests were based on colorimetric visualization and/or precipitate formation after the addition of specific reagents.…”

Biogenic Zinc oxide nanoparticles from Celosia argentea : Toward improved antioxidant, antibacterial and anticancer activities

“…Several ailments, including jaundice, inflammation, wound healing, eye diseases, and glandular swellings, had long been treated with C. argentea in traditional medicine. Numerous studies on C. argentea's anticancer mechanism have shown evidence that it causes cells to commit suicide through apoptosis [17][18][19] .…”