PLoS ONE volume 9, issue 5, Pe98277 2014 DOI: 10.1371/journal.pone.0098277 View full text
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Sara Leijon, Anna K. Magnusson

Abstract: The functional role of efferent innervation of the vestibular end-organs in the inner ear remains elusive. This study provides the first physiological characterization of the cholinergic vestibular efferent (VE) neurons in the brainstem by utilizing a transgenic mouse model, expressing eGFP under a choline-acetyltransferase (ChAT)-locus spanning promoter in combination with targeted patch clamp recordings. The intrinsic electrical properties of the eGFP-positive VE neurons were compared to the properties of th…

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