Arch Gen Psychiatry
 1975
DOI: 10.1001/archpsyc.1975.01760200101010
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Physiological and Psychological Effects of Methadone in Man

Ellen R. Gritz1
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Cited by 81 publications

(54 citation statements)
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“…The present study did not confirm slowing of α-rhythm in withdrawal opioid addicts reported earlier (Gritz, et al, 1975;Gekht, et al, 2003). The increase in the percentage of fast-α-rhythmic EEG segments during early withdrawal in the pres- Figure 4 The maximum periods of temporal stabilization: (A) for each spectral pattern type, which was found in the EEG probability-classification profiles.…”
Section: Characteristics Of Eeg Changes Induced By Early Withdrawalcontrasting
confidence: 99%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…The present study did not confirm slowing of α-rhythm in withdrawal opioid addicts reported earlier (Gritz, et al, 1975;Gekht, et al, 2003). The increase in the percentage of fast-α-rhythmic EEG segments during early withdrawal in the pres- Figure 4 The maximum periods of temporal stabilization: (A) for each spectral pattern type, which was found in the EEG probability-classification profiles.…”
Section: Characteristics Of Eeg Changes Induced By Early Withdrawalcontrasting
confidence: 99%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…The current study investigated the effect of MMT on neurophysiological function by comparing the resting state gamma power of patients undergoing MMT with current opiate users and healthy volunteers. Our results are in good accordance with the majority of human EEG studies focusing on the effects of opiates on neurophysiological function, 3,27,28 and indicate that long-term exposure to opioid-type drugs is associated with a disrupted resting state network. It has been suggested that resting state EEG represents the readiness or "potential" of the brain to allocate neural resources essential to cognitive function, for example, information processing and attention, 29 Spontaneous gamma activity that contribute a fraction of the total EEG power is driven by thalamocortical resonant synaptic interactions 11 and reflects an integration mechanism of the brain.…”
Section: Discussionsupporting
confidence: 89%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“……”
Section: Topological Aspects Of Functional Connectivitysupporting
confidence: 94%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
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