DOI: 10.1016/j.phrs.2020.104833
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Abstract: The renin-angiotensin system (RAS) is crucial for the physiology and pathology of all the organs. Angiotensinconverting enzyme 2 (ACE2) maintains the homeostasis of RAS as a negative regulator. Recently, ACE2 was identified as the receptor of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the coronavirus that is causing the pandemic of Coronavirus disease 2019 (COVID-19). Since SARS-CoV-2 must bind with ACE2 before entering the host cells in humans, the distribution and expression of ACE2 may be…

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