Physical Functioning, Pain, and Health‐Related Quality of Life in Adults With Juvenile Idiopathic Arthritis: A Longitudinal 30‐Year Followup Study

Abstract

JIA had a detrimental effect on physical HRQoL as measured by the PCS of the SF-36. The strongest correlates were physical disability, pain, fatigue, well-being, and receiving disability/social living allowance.

Early Self‐Reported Pain in Juvenile Idiopathic Arthritis as Related to Long‐Term Outcomes: Results From the Nordic Juvenile Idiopathic Arthritis Cohort Study

“…Self‐reported, disease‐related pain intensity during the previous week was measured on a 10‐cm VAS for pain (where 0 = no pain and 10 = worst possible pain) by the child if age ≥9 years or by the parents if the child was age <9 years. VAS pain was assessed with the question “How do you rate your/your child's pain due to your/his or her illness in the past week?” As in previous studies on pain in JIA , pain analyses were explored both by categorization of VAS pain (0, >0 to 3, >3 to 7, or >7 to 10), and dichotomized into 0 (no pain) or >0. We performed subanalyses on VAS pain scores in participants age <9 years and ≥9 years to look for any discrepancies between parent‐ and patient‐reported pain .…”

“…Damage was defined as either JADI‐A and/or JADI‐E score >0. As in previous studies, C‐HAQ/HAQ and JADI scores were dichotomized into 0 (no disability, no damage) or >0 . Physical and psychosocial summary scores of the CHQ were dichotomized into <40 (poor health) or ≥40 (better health) .…”

“…The pathogenesis of pain in children and adolescents with JIA is multifactorial, including both biologic and psychosocial factors . Pain is a distressing symptom, and several studies have elucidated the relationship between pain, functional disability, and health‐related quality of life , but information about pain as a predictor of long‐term disease outcome is lacking.…”

Health‐related quality of life in children with early‐stage juvenile idiopathic arthritis

“…Juvenile idiopathic arthritis (JIA) is the most common chronic acquired arthritis in children (Petty et al, ). The disease can impair both physical and psychosocial functions, resulting in developmental delays and chronic disability (Hanns et al, ; Magni‐Manzoni et al, ; Moorthy, Peterson, Hassett, & Lehman, ; Tollisen et al, ). Furthermore, emotional and school difficulties are major concerns in children with JIA (Bomba et al, ).…”

A Canadian evaluation framework for quality improvement in childhood arthritis: key performance indicators of the process of care

“…In a Norwegian study, after 30 years of follow-up, persistence of active disease or medication use was seen in 41% of patients with JIA, with up to 28% having a high symptom state [6]. Consequences of inadequately treated disease include pain, functional limitations due to joint deformities or damage, growth abnormalities, and psychological impacts [7,8]. Beyond the burden on patients and families, JIA can also be a costly disease.…”