JAMA
 2008
DOI: 10.1001/jama.300.9.1077
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Physical Activity for Older Adults at Risk for Alzheimer Disease

Eric B. Larson1
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Cited by 47 publications

(32 citation statements)
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“…Consistent with previous reports demonstrating that regular exercise can improve cognitive function in aging as well as diseased populations, (Cotman and Berchtold, 2002; Kramer and Erickson, 2007; Larson, 2008), we showed that regular exercise had a beneficial effect on memory in previously sedentary but otherwise healthy, young adults. However, this was only true for participants who exercised on the final day of testing after the 4-week exercise intervention (i.e., the 4W+ group).…”
Section: Discussionsupporting
confidence: 92%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…Consistent with previous reports demonstrating that regular exercise can improve cognitive function in aging as well as diseased populations, (Cotman and Berchtold, 2002; Kramer and Erickson, 2007; Larson, 2008), we showed that regular exercise had a beneficial effect on memory in previously sedentary but otherwise healthy, young adults. However, this was only true for participants who exercised on the final day of testing after the 4-week exercise intervention (i.e., the 4W+ group).…”
Section: Discussionsupporting
confidence: 92%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…Δ t2-t1 was significantly different between group 1 (dance) and group 2 (care as usual) (median group1 - t 1 28 [6–49], median group1 - t 2 27 [7–33], median group2 - t 1 19 [13–35], median group2 - t 2 25 [14…”
Section: Resultsmentioning
confidence: 99%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…Interestingly, older age at retirement is associated with lower risk of mental disorders namely, decreased risk of dementia and Alzheimer Disease [27] [28]. Loss of work ability and work life years could be much higher than anticipated in industrialized regions, where proportionally more physical labor is expected in the work force [29].…”
Section: Discussionmentioning
confidence: 99%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
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