Physical Activity and Sedentary Time: Association with Metabolic Health and Liver Fat

Davies, Kelly A Bowden; Sprung, Victoria S.; Norman, J; Thompson, Andrew; Mitchell, Katie; Harrold, Joanne; Finlayson, Graham; Gibbons, Catherine; Wilding, John; Kemp, Graham J.; Hamer, Mark; Cuthbertson, Daniel J.

doi:10.1249/mss.0000000000001901

Cited by 44 publications

(45 citation statements)

References 47 publications

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“…In the second study [28], IL-6 was also increased and after returning to normal activity, inflammatory markers were still elevated. In contrast, in the studies conducted in young individuals, no changes were produced in inflammatory parameters [20,22,25,26].…”

Section: Detrimental Health Effects Of An Acute Sedentary Lifestyle Imentioning

confidence: 75%

“…Other authors have looked at what happens when a reduction in physical activity and overfeeding are accompanied by an exercise intervention [26]. Over one week, 26 physically active men (25 (7) years; BMI 23.8 (2.5)) were randomly assigned to two groups.…”

Section: Metabolic Effects Of Acute Physical Inactivity Plus Overfeedingmentioning

confidence: 99%

“…As the main limitation of the studies reviewed, with the exception of three studies [24,26,28] (n = 45, n = 26, n = 22, respectively), most had <20 participants, so statistical power was low. Participants were mainly males (n = 119) and there was a lower number of females (n = 51).…”

Section: Limitationsmentioning

confidence: 99%

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Metabolic Impacts of Confinement during the COVID-19 Pandemic Due to Modified Diet and Physical Activity Habits

et al. 2020

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While the detrimental effects of a chronic positive energy balance due to a sedentary lifestyle have been well established, the impacts of a short period of abruptly reduced physical activity and overeating arising from strict confinement due to the COVID-19 pandemic will soon start to emerge. To reasonably anticipate major consequences according to the available evidence, we hereby review the literature for studies that have explored the health impacts of several weeks of a reduction in physical activity and daily step-count combined with modified eating habits. These studies identify as main metabolic consequences increases in insulin resistance, total body fat, abdominal fat and inflammatory cytokines. All these factors have been strongly associated with the development of metabolic syndrome, which in turn increases the risk of multiple chronic diseases. A plausible mechanism involved in these impacts could be a positive energy balance promoted by maintaining usual dietary intake while reducing energy expenditure. This means that just as calorie intake restriction could help mitigate the deleterious impacts of a bout of physical inactivity, overeating under conditions of home confinement is very likely to exacerbate these consequences. Moreover, hypertension, diabetes, and cardiovascular disease have been identified as potential risk factors for more severely ill patients with COVID-19. Thus, adequate control of metabolic disorders could be important to reduce the risk of severe COVID-19.

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Section: Detrimental Health Effects Of An Acute Sedentary Lifestyle Imentioning

confidence: 75%

Section: Metabolic Effects Of Acute Physical Inactivity Plus Overfeedingmentioning

confidence: 99%

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Metabolic Impacts of Confinement during the COVID-19 Pandemic Due to Modified Diet and Physical Activity Habits

et al. 2020

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“…Otherwise, leisure time activities of teachers may be more susceptible to sedentary choices, as television viewing, computer and cellphone use, and consequently be significantly affected by sedentary breaks at this domain. Another factor is that sedentary behavior has been associated with unhealthy metabolic health, regardless of physical activity levels 39) and high sedentary breaks at leisure may be able to mitigate the health impairments of sedentary behavior by reducing its accumulation in longer periods and by decreasing the sedentary time overall. Healy et al…”

Section: Discussionmentioning

confidence: 99%

Association between sedentary behavior, obesity and hypertension in public school teachers

Delfino

Tebar

et al. 2020

Ind Health

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The present study aimed to verify the prevalence and association of sedentary behavior and its breaks with obesity and cardiovascular risk factors in teaching professionals. The sample was composed by 245 public school teachers (186 women and 59 men), with a mean age of 45 years. Sedentary behavior was evaluated by self-reported screen time in different devices (television, computer, cellphone/tablet), and sedentary breaks at work and leisure were assessed by a Likert scale (never, rarely, sometimes, often, always). Cardiovascular risk factors (overweight/obesity, abdominal obesity, blood pressure, and heart rate) were objectively collected by trained individuals in the work environment of the teachers. Logistic Binary Regression models were adjusted for confounding factors (age, sex, and socioeconomic status). The prevalence of sedentary behavior was 55.3% in the sample. High sedentary behavior was associated to abdominal obesity (OR=2.21[CI=1.23-3.97]). No association was observed between sedentary breaks at work and independent variables, however teachers with high sedentary breaks at leisure time were less likely to present high blood pressure (OR=0.58[CI=0.32-0.98]). In conclusion, high sedentary behavior was associated with abdominal obesity, and high sedentary breaks in leisure time were associated to lower chances of high blood pressure among public school teachers.

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“…18,20 A study was conducted in the UK to investigate the effect of physical activity and sedentary time on metabolic health and liver adiposity. 21 Results revealed that greater time spent in sedentary was associated with MetS, independent of physical activity levels. More recently, cross-sectional data suggested that high level of sedentary time was associated with poorer glycemic control in people with type 2 diabetes mellitus.…”

Section: Introductionmentioning

confidence: 89%

<p>Associations of Physical Activity and Sedentary Time with Metabolic Syndrome in Saudi Adult Males</p>

Aljuhani¹,

Alkahtani²,

Alhussain³

et al. 2020

RMHP

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The association between objectively measured sedentary behavior and physical activity with metabolic syndrome (MetS) has been rarely investigated in Saudi Arabia. The purpose of the current study was to examine the association of objectively measured sedentary, light physical activity (LPA), and moderate-vigorous physical activity (MVPA) with MetS among Saudi adult males. Materials and Methods: The study participants were 103 males from Riyadh, Saudi Arabia (mean age = 54.9 ± 10.6 years). Metabolic syndrome was defined based on having three or more of cardiometabolic risk factors. Triaxial accelerometers were used to measure the time spent on sedentary and physical activities across 7 days. A minimum four days with ≥10 hours of wearing time per day were considered a valid data. Binary logistics regression models were performed to examine the association of sedentary and physical activity levels with MetS vs no MetS. Model 1 was unadjusted, models 2, 3, and 4 were mutually controlled for sedentary, light, and MVPA intensities. Results: About 38% of males in the present study were classified as having MetS as demonstrated by a significant (p<0.05) decrease in high-density lipoprotein cholesterol (HDL-C) and a significant (p<0.05) increase in body weight, body mass index (BMI), waist circumference (WC), systolic blood pressure, glucose, and triglycerides compared to those without MetS. In addition, low levels of LPA (less than 6.3 hours per day) were significantly associated with the risk of having MetS, independent of sedentary and MVPA (odds ratio (OR) 4.26-6.96). The results showed that the associations between sedentary tertiles and MetS were not statistically significant. Levels of MVPA were also not significantly associated with an increased risk of developing MetS in all models. Conclusion: This study showed that low levels of LPA were significantly associated with the risk of having MetS in Saudi males from Riyadh city, independent of MVPA and sedentary time. The results suggest that future intervention studies should assess the positive effect of increasing levels of LPA in reducing the risk of developing MetS in males.

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Physical Activity and Sedentary Time: Association with Metabolic Health and Liver Fat

Cited by 44 publications

References 47 publications

Metabolic Impacts of Confinement during the COVID-19 Pandemic Due to Modified Diet and Physical Activity Habits

Metabolic Impacts of Confinement during the COVID-19 Pandemic Due to Modified Diet and Physical Activity Habits

Association between sedentary behavior, obesity and hypertension in public school teachers

<p>Associations of Physical Activity and Sedentary Time with Metabolic Syndrome in Saudi Adult Males</p>

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