Physical activity and healthy aging

Cano, Antonio

doi:10.1097/gme.0000000000000649

Cited by 7 publications

(6 citation statements)

References 4 publications

(3 reference statements)

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“…This phenomenon can lead to decreased physical activity and can increase the risk of falls in aged individuals 2 . Therefore, it is important to understand the mechanisms underlying aging-induced skeletal muscle atrophy in order to develop suitable therapeutic targets to promote health and mobility in the elderly 3 .…”

Section: Introductionmentioning

confidence: 99%

Age-related changes in skeletal muscle mitochondria: the role of exercise

Seo

Lee

Kim

et al. 2016

Integrative Medicine Research

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Aging is associated with mitochondrial dysfunction, which leads to a decline in cellular function and the development of age-related diseases. Reduced skeletal muscle mass with aging appears to promote a decrease in mitochondrial quality and quantity. Moreover, mitochondrial dysfunction adversely affects the quality and quantity of skeletal muscle. During aging, physical exercise can cause beneficial adaptations to cellular energy metabolism in skeletal muscle, including alterations to mitochondrial content, protein, and biogenesis. Here, we briefly summarize current findings on the association between the aging process and impairment of mitochondrial function, including mitochondrial biogenesis and reactive oxygen species in skeletal muscle. We also discuss the potential role of exercise in the improvement of aging-driven mitochondrial dysfunctions.

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Section: Introductionmentioning

confidence: 99%

Age-related changes in skeletal muscle mitochondria: the role of exercise

Seo

Lee

Kim

et al. 2016

Integrative Medicine Research

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“…By contrast, HDL‐C correlated positively with DEE but negatively with TEI. One study found that physical inactivity increased the risk of coronary death by 1.9‐fold . Undertaking moderate exercise (30 minutes of brisk walking per day) both promoted weight loss and improved components of MetS …”

Section: Discussionmentioning

confidence: 99%

Prevalence of metabolic syndrome and its association with lifestyle and cardiovascular biomarkers among postmenopausal women in western Algeria

Khalfa

Tiali

Zemour

et al. 2017

Intl J Gynecology & Obste

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“…In this sense, this study reflects that a well-designed and specific multicomponent exercise program in this population is an important tool to consider and to promote, especially in women for whom the use of pharmacology is not clearly justified. 55…”

Section: Exercise and Menopause-related Symptomsmentioning

confidence: 99%

A 16-week multicomponent exercise training program improves menopause-related symptoms in middle-aged women. The FLAMENCO project randomized control trial

et al. 2022

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Objective: To investigate the influence of a supervised multicomponent exercise training program on menopause-related symptoms, particularly vasomotor symptoms (VMS), in middle-aged women.Methods: A total of 112 middle-aged women (mean age 52 AE 4 y old, age range 45-60 y) from the FLAMENCO project (exercise [n ¼ 59] and counseling [n ¼ 53] groups) participated in this randomized controlled trial (perprotocol basis). The exercise group followed a multicomponent exercise program composed of 60-minute sessions 3 days per week for 16 weeks. The 15-item Cervantes Menopause and Health Subscale was used to assess the frequency of menopause-related symptoms.Results: After adjusting for body mass index and Mediterranean diet adherence, the subscales measuring menopause-related symptoms and VMSs decreased 4.6 more in the exercise group compared to the counseling group (between-group differences [B]: 95% CI: -8.8 to -0.2; P ¼ 0.040). The exercise group also showed significant improvements in the subscales of couple relationships (between-group differences [B]: -1.87: 95% CI: -3.29 to -0.45; P ¼ 0.010), psychological state (between-group differences [B]: -2.3: 95% CI: -5 to -0.2; P ¼ 0.035), and VMSs (between-group differences [B]: -4.5: 95% CI: -8.8 to -0.2; p ¼ 0.040) in the Cervantes Menopause and Health Subscale compared with the counseling group.Conclusions: A 16-week multicomponent physical exercise program showed a positive effect on menopauserelated symptoms especially in couple relationships, psychological state, and VMS, among 45 to 60 year old women.

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Physical activity and healthy aging

Cited by 7 publications

References 4 publications

Age-related changes in skeletal muscle mitochondria: the role of exercise

Age-related changes in skeletal muscle mitochondria: the role of exercise

Prevalence of metabolic syndrome and its association with lifestyle and cardiovascular biomarkers among postmenopausal women in western Algeria

A 16-week multicomponent exercise training program improves menopause-related symptoms in middle-aged women. The FLAMENCO project randomized control trial

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