Photosensitizing potential of certain nonsteroidal anti-inflammatory agents

Kaidbey, K. H.

doi:10.1001/archderm.125.6.783

Archives of Dermatology

1989

DOI: 10.1001/archderm.125.6.783

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Photosensitizing potential of certain nonsteroidal anti-inflammatory agents

K. H. Kaidbey¹

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Cited by 15 publications

(9 citation statements)

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6

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“…The phototoxicity of a wide range of NSAIDs has also been assessed in healthy subjects, who had received nabumetone, naproxen, ketoprofen and piroxicam, and the skin response to radiation was compared with that observed in placebo-treated subjects [11]. Only nabumetone and naproxen were shown to induce any phototoxicity, which in all cases was mild and occurred at the end of the dosing period, immediately after irradiation.…”

Section: Discussionmentioning

confidence: 99%

Lack of photosensitising potential of tenidap, a novel anti‐rheumatic agent.

Ferguson

¹

,

Leeming

²

1995

Brit J Clinical Pharma

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Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.

“…The phototoxicity of a wide range of NSAIDs has also been assessed in healthy subjects, who had received nabumetone, naproxen, ketoprofen and piroxicam, and the skin response to radiation was compared with that observed in placebo-treated subjects [11]. Only nabumetone and naproxen were shown to induce any phototoxicity, which in all cases was mild and occurred at the end of the dosing period, immediately after irradiation.…”

Section: Discussionmentioning

confidence: 99%

Lack of photosensitising potential of tenidap, a novel anti‐rheumatic agent.

Ferguson

¹

,

Leeming

²

1995

Brit J Clinical Pharma

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Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.

“…However, in vitro and in vivo studies have not shown that piroxicam has phototoxic potential (Serrano et al 1984;Kaidbey and Mitchell 1989). Though the possibility of a photoallergic mechanism seems more likely, this interval between treatment start and photoreaction is shorter than can be accepted if the reaction represented a primary photoallergic sensitization to piroxicam.…”

Section: Discussionmentioning

confidence: 99%

Photocontact Dermatitis Due to Piroxicam: Photopatch Testing.

Torinuki

¹

1992

Tohoku J. Exp. Med.

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Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.

“…The mechanism of the reaction pattern, either photoallergy or phototoxicity, is not established [4][5][6][7]. Rashes are usu ally vesiculobullous, but they may be maculopapular.…”

Section: Discussionmentioning

confidence: 99%

Systemic Lupus erythematosus Exacerbated by Piroxicam

Roura

¹

,

López-Gil

²

,

Umbert

³

1991

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Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.

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