Photorefractive Keratectomy Following Penetrating Keratoplasty

Abstract

We present 3 eyes that underwent photorefractive keratectomy (PRK) for residual myopia after penetrating keratoplasty, and 1 eye that was treated for recurrent granular dystrophy and myopia following penetrating keratoplasty. The 3 refractive eyes experienced improvements in visual acuity and refractive error through 3 months postoperative, but exhibited regression of effect after 6 months postoperative. One eye also exhibited substantial corneal haze at three months postoperative that was not responsive to steroid retreatment. The eye with granular dystrophy obtained symptomatic relief as well as improvement in vision. We tentatively conclude that the corneal transplant reacts to photorefractive keratectomy in much the same way as a normal cornea. Eyes with substantial degrees of post-graft myopia exhibit regression of refractive effect, much like high myopes following primary photorefractive keratectomy. Photorefractive was unable to prevent the recurrence of granular dystrophy in the transplanted tissue. The eyes reported here achieved only modest long-term visual and refractive improvements. [J Refract Corneal Surg. 1994:10:S206S210.]

Long term analysis of lasik for the correction of refractive errors after penetrating keratoplasty

“…The results of photorefractive keratectomy (PRK) performed in this setting have been published in different studies, many of them reporting a significant incidence of stromal haze. 11,15,21,24,27,31,36,40 The haze appears to be related to the large magnitude of the ablations necessary for these cases, and it is usually coupled with regression of the obtained refractive effect and loss of best spectacle-corrected visual acuity (BCVA). In addition there are some case reports of graft rejection induced by excimer photoablation.…”