Journal of Cell Biology volume 216, issue 5, P1489-1499 2017 DOI: 10.1083/jcb.201608081 View full text
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Raquel Y. Salinas, Jillian N. Pearring, Jin-Dong Ding, William J. Spencer, Ying Hao, Vadim Y. Arshavsky

Abstract: Visual signal transduction occurs on the surface of membrane discs stacked inside the ciliary outer segment of photoreceptor cells. Salinas et al. show that discs are formed from ciliary ectosomes whose release is blocked by the protein peripherin/RDS. This explains how photoreceptors transform their primary cilia into the light-sensing outer segment organelle.