Photoprotective properties of Prunella vulgaris and rosmarinic acid on human keratinocytes

Ultraviolet Light Induced Alteration to the Skin

“…To date only few substances/extracts have been demonstrated to be capable of protecting/suppressing UVA-induced skin cells/ skin injury e.g. carnosic acid 71 , quercetin 72 , epikatechin 74 , epigallokatechin-3-gallate 74,75 or P. leucotomos extract 76 , silymarin 77 and P. vulgaris extract 78 . Considering the latest knowledge about UV radiation it is necessary to look for new substances possessing both UVA and UVB protection.…”

Effects of ammonium to nitrate ratio on growth, nitrogen metabolism, photosynthetic efficiency and bioactive phytochemical production ofPrunella vulgaris

“…Prunellae Spica, the dried spica of P. vulgaris, is a standard medicinal material in the Chinese Pharmacopoeia (Chinese Pharmacopoeia Commission, 2010). It is a well-known Chinese medicinal herb used to reduce fever, alleviate sore throat, and accelerate wound healing (Chen et al, 2011;Pinkas et al, 1994;Psotová et al, 2003Psotová et al, , 2006. It is also commonly used as a traditional medicinal herb in some Asian and Europe countries, such as Korea, Japan, Turkey, the Czech Republic, Poland, and Germany (Chen et al, 2013).…”

“…Rosmarinic acid (RA), one of the phenolic acids found in P. vulgaris, suppresses lipoperoxidation, scavenges superoxide radicals, and exhibits antiinflammatory and antioxidant bioactivities (Psotová et al, 2006). Rosmarinic acid content has been used as the criterion for quality control of Prunellae Spica in the Chinese Pharmacopoeia (Chinese Pharmacopoeia Commission, 2010).…”

Anti-Aging Cosmetics Approaches and Components in Products

“…Prunella vulgaris'in yapısında fenolik yapıda olan rosmarinik asit bulunmaktadır ve fotoprotektif ajan olarak kullanılmaktadır. Rosmarinik asit hücreler arası lipit peroksidasyonunu azaltmakta ve UVA'nın reaktif oksijen türlerini artırıcı etkilerini önemli oranda baskılamaktadır 72 . Sophora japonica bitkisinde yüksek antioksidan özellikte olan kersetin bulunmaktadır ve ciltte meydana gelebilecek UVB kaynaklı oksitatif hasarı ortadan kaldırmaya yardımcı olmaktadır 73 .…”