Photonic Crystal Waveguide Sensing

Skibina, Julia S.; Malinin, A. V.; Zanishevskaya, Anastasiya A.; Tuchin, Valery V.

doi:10.1201/b15589-2

Cited by 7 publications

(4 citation statements)

References 45 publications

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“…The diameter of the central capillary is 194 µm, the thickness of the walls for 1, 2, 3, 4 and 5th layer of capillaries are 1.8, 2.6, 3.3, 4.1, and 4.7 µm, the diameters of the capillaries belonging to 1, 2, 3, 4 and 5th layer are 14, 19, 25, 31, and 35 µm, respectively. Spectral properties for this kind of HC-MFs were discussed in detail in [25][26][27]. Figure 1 shows the HC-MF and the scheme of the coating formation.…”

Section: Preparation Of Samplesmentioning

confidence: 99%

Enabling magnetic resonance imaging of hollow-core microstructured optical fibers via nanocomposite coating

Noskov

Zanishevskaya²,

Shuvalov³

et al. 2019

Opt. Express

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Optical fibers are widely used in bioimaging systems as flexible endoscopes that are capable of low-invasive penetration inside hollow tissue cavities. Here, we report on the technique that allows magnetic resonance imaging (MRI) of hollow-core microstructured fibers (HC-MFs), which paves the way for combing MRI and optical bioimaging. Our approach is based on layer-by-layer assembly of oppositely charged polyelectrolytes and magnetite nanoparticles on the inner core surface of HC-MFs. Incorporation of magnetite nanoparticles into polyelectrolyte layers renders HC-MFs visible for MRI and induces the red-shift in their transmission spectra. Specifically, the transmission shifts up to 60 nm have been revealed for the several-layers composite coating, along with the high-quality contrast of HC-MFs in MRI scans. Our results shed light on marrying fiber-based endoscopy with MRI to open novel possibilities for minimally invasive clinical diagnostics and surgical procedures in vivo.

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Section: Preparation Of Samplesmentioning

confidence: 99%

Enabling magnetic resonance imaging of hollow-core microstructured optical fibers via nanocomposite coating

Noskov

Zanishevskaya²,

Shuvalov³

et al. 2019

Opt. Express

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show abstract

“…Starting from the first realization of microstructured optical fibers (MOFs) over twenty years ago [1,2], they have found numerous applications in optics [3], optogenetics [4], life science [5], plasmonics [6,7], and related fields [8,9]. Among others, biomedicine and biochemistry with their increasing demand for fast, precise, and easy sensing techniques became major stimuli for the development of optical fiber-based sensors (OFSs).…”

Section: Introductionmentioning

confidence: 99%

Functionalized Microstructured Optical Fibers: Materials, Methods, Applications

et al. 2020

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Microstructured optical fiber-based sensors (MOF) have been widely developed finding numerous applications in various fields of photonics, biotechnology, and medicine. High sensitivity to the refractive index variation, arising from the strong interaction between a guided mode and an analyte in the test, makes MOF-based sensors ideal candidates for chemical and biochemical analysis of solutions with small volume and low concentration. Here, we review the modern techniques used for the modification of the fiber’s structure, which leads to an enhanced detection sensitivity, as well as the surface functionalization processes used for selective adsorption of target molecules. Novel functionalized MOF-based devices possessing these unique properties, emphasize the potential applications for fiber optics in the field of modern biophotonics, such as remote sensing, thermography, refractometric measurements of biological liquids, detection of cancer proteins, and concentration analysis. In this work, we discuss the approaches used for the functionalization of MOFs, with a focus on potential applications of the produced structures.

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“…Here, the analyte fills one or several fiber capillaries, serving as a part of the probed resonator, and the optical resonances of these fluid-filled channels are probed. The major benefit of using MOWs rather than equivalent techniques based on cuvettes and bulk optics lies in combining the long interaction lengths with strong overlapping between light and the analyte within small sample volumes, giving rise to high sensitivity [37][38][39][40].…”

Section: Introductionmentioning

confidence: 99%

Microstructured Optical Waveguide-Based Endoscopic Probe Coated with Silica Submicron Particles

et al. 2019

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Microstructured optical waveguides (MOW) are of great interest for chemical and biological sensing. Due to the high overlap between a guiding light mode and an analyte filling of one or several fiber capillaries, such systems are able to provide strong sensitivity with respect to variations in the refractive index and the thickness of filling materials. Here, we introduce a novel type of functionalized MOWs whose capillaries are coated by a layer-by-layer (LBL) approach, enabling the alternate deposition of silica particles (SiO2) at different diameters—300 nm, 420 nm, and 900 nm—and layers of poly(diallyldimethylammonium chloride) (PDDA). We demonstrate up to three covering bilayers consisting of 300-nm silica particles. Modifications in the MOW transmission spectrum induced by coating are measured and analyzed. The proposed technique of MOW functionalization allows one to reach novel sensing capabilities, including an increase in the effective sensing area and the provision of a convenient scaffold for the attachment of long molecules such as proteins.

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Photonic Crystal Waveguide Sensing

Cited by 7 publications

References 45 publications

Enabling magnetic resonance imaging of hollow-core microstructured optical fibers via nanocomposite coating

Enabling magnetic resonance imaging of hollow-core microstructured optical fibers via nanocomposite coating

Functionalized Microstructured Optical Fibers: Materials, Methods, Applications

Microstructured Optical Waveguide-Based Endoscopic Probe Coated with Silica Submicron Particles

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