MEMS devices come in a bewildering variety, in regard to structures, materials and functions. Whereas all CMOS technologies are close relatives, MEMS devices are made with a multitude of closely related, distantly related and unrelated technologies. Pressure sensor operation can be based on piezoresistive, capacitive, thermal conductance or resonance mechanisms, and while the first three share some structural features and fabrication steps, the fourth bears more resemblance to gyroscopes and RF oscillators. Accelerometers are made of single crystal silicon, of bulk, epitaxial and SOI type, of polycrystalline silicon and of electroplated metals. Electrospray emitters have been realized in silicon, glass, quartz, SU-8, PDMS, PMMA and many other polymers. Microneedles have been made in both out-of-plane and in-plane configurations, from single crystal and polysilicon, silicon dioxide, metals, polymers. Micromirrors are most often made of silicon, but also of metals or metallized nitride membranes. Mirrors come in in-plane (horizontal) and out-of-plane (vertical) versions too.Bulk and SOI MEMS structures have high aspect ratios and highly complex 3D shapes resulting from etching and wafer bonding. These put new requirements on subsequent lithography, doping and thin-film steps, and introduce novel metrology requirements. MEMS devices with through-wafer holes pose process limitations: for instance, in spinning a vacuum chuck holds the wafer, and DRIE reactors use backside helium cooling. Through-wafer structures require double-sided processing and even without through-holes, there is often a need to align structures on the two sides of the wafer. Double-sided alignment is also mandatory for structured wafer bonding.MEMS devices are not solid state devices: they have free-standing, moving, rotating and vibrating structures, like the grids of old-fashioned vacuum tubes. These moving structures create challenges for the subsequent processing and packaging steps. Capillary forces in drying, silicon dust and vibrations during dicing, or stresses in encapsulation may damage delicate mechanical structures. Closed cavities can sometimes be handled without problems, but high temperatures and changing pressures during fabrication can cause some design limitations, especially when the cavity roof is a thin diaphragm. Despite this seeming variety, there are many generic structures, design principles and widely used techniques for realizing them. These are the topics of this chapter.