Abstract:Hsp47 is a chaperone protein with a fundamental
role in the folding, stability and intracellular transport of procollagen
triple helices. A light-responsive Hsp47 recombinant protein, engineered to
control in situ the production and assembly of cellular collagen is here
demonstrated. This novel light-driven tool enables unprecedented fundamental
studies of collagen biosynthesis and associated diseases.
Set email alert for when this publication receives citations?
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.