Phonatory outcome of 585nm/pulsed-dye laser in the management of glottic leukoplakia

Park, Young Min; Jo, Kwang Hee; Hong, Hyeyoung; Choi, Hong‐Shik

doi:10.1016/j.anl.2014.05.013

Cited by 21 publications

(30 citation statements)

References 17 publications

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“…Since the initial attempt of McMillan et al of applying PDL in treating laryngeal papillomas [ 14 , 15 ], there have been numerous reports of PDL application in the management of leukoplakia, glottic dysplasia, granuloma, and vascular abnormalities of the vocal folds [ 16 – 19 ]. The utility of the PDL has been further verified with the treatment of glottic hyperkeratosis and sulcus vocalis by Choi et al [ 8 , 9 ].…”

Section: Discussionmentioning

confidence: 97%

“…The chromophore of the PDL is oxyhemoglobin, resulting in the laser inducing photocoagulation of microvascular lesions with minimal damage to the surrounding normal tissue. Based on our recent successful reports of PDL application in treating sulcus vocalis and glottic leukoplakia [ 8 , 9 ], we have managed to use PDL in surgically removing hemorrhagic vocal polyps. This study aims to report our surgical technique, PDL-assisted enucleation laryngomicrosurgery (LMS), which can effectively resect the polyp with vocal fold mucosa preservation.…”

Section: Introductionmentioning

confidence: 99%

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Treatment of Hemorrhagic Vocal Polyps by Pulsed Dye Laser-Assisted Laryngomicrosurgery

Byeon

Han

Choi

et al. 2015

BioMed Research International

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Objective. Conventional surgical techniques of laryngomicrosurgery (LMS) on hemorrhagic vocal polyps are often difficult due to obscuration of the surgical field by inadvertent bleeding from the lesion, and there are often significant amounts of mucosal epithelium loss. Here, we introduce our surgical technique using pulsed dye laser (PDL), which can effectively resect the polyp with vocal fold mucosa preservation. Methods. Patients who were diagnosed with hemorrhagic vocal polyp and who were surgically managed using PDL from March 2013 to October 2014 were retrospectively reviewed. Preoperative and postoperative clinical outcomes and surgical findings were evaluated. Results. A total of 39 patients were treated with PDL-assisted enucleation LMS. The average age was 43.7 years (range 20–73), and there were 20 males and 19 females (17 professional voice users). In all cases, the hemorrhagic polyp was successfully enucleated after application of PDL, thereby preserving the overlying epithelium. Postoperative voice outcomes were favorable with clear preservation of the vocal fold mucosal wave. Conclusion. PDL-assisted enucleation LMS for the treatment of hemorrhagic vocal polyps can be a safe and effective surgical technique. It can be considered a promising treatment option for hemorrhagic vocal polyps.

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Section: Discussionmentioning

confidence: 97%

Section: Introductionmentioning

confidence: 99%

Treatment of Hemorrhagic Vocal Polyps by Pulsed Dye Laser-Assisted Laryngomicrosurgery

Byeon

Han

Choi

et al. 2015

BioMed Research International

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“…Therefore, the application of 585-nm PDL to benign vocal cord disease have been reported and suggested that PDL is superior to CO2 laser. 8,13 The mechanism to remove a tissue with the PDL is photocoagulation of submucosal microcircula-tion. In particular, PDL denatures basement membrane anchoring fibers located in the lamina lucida of the basement membrane through a photoacoustic or photothermal effect and creates a cleavage plane between the epithelium and superficial lamina propria.…”

Section: Discussionmentioning

confidence: 99%

“…7 Recently, clinical applications of 585-nm Pulse-Dye Laser (PDL) and 532-nm Potassium-Titanyl-Phosphate (KTP) lasers for laryngeal Reinke's edema have reported. 8,9 These two lasers with the similar wavelength are angiolytic laser that was developed based on the concept of selective photothermolysis, which allows for photocoagulation of microvascular lesions and minimal injury of the surrounding tissues.…”

Section: Introductionmentioning

confidence: 99%

Treating Oral Leukoplakia with a 532-nm Pulsed Diode Laser

Kim

et al. 2019

Medical Lasers

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A 50-year-old Korean female with oral erythro-leukoplakia was treated using a 532-nm Diode laser at 6 Watts with a pulsed width of 25 milliseconds. After two months following the laser treatment, the resected region was well-healed without any significant scar contracture. We suggest that the use of the 532-nm Diode laser can be a safe and effective treatment modality for patients suffering from oral leukoplakia.

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“…Angiolytic irradiation and stripping were performed as described previously [6]. In brief, after evaluation of the magnified vocal fold leukoplakia lesions under general anesthesia, a flexible laser fiber was inserted for transmission of the angiolytic laser.…”

Section: Methodsmentioning

confidence: 99%

Angiolytic laser stripping versus CO2 laser microflap excision for vocal fold leukoplakia: Long-term disease control and voice outcomes

et al. 2018

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Background and purposeVocal fold leukoplakia, white plaque on the epithelium, has the potential for malignant transformation regardless of dysplasia grade. It is treated with different laser types (CO2 or angiolytic) and various techniques (vaporization, stripping, or excision); however, only a few studies exist regarding comparative laser surgery results. This study was conducted to investigate clinical outcomes of CO2 versus angiolytic laser microdissection with regard to long-term disease control and voice preservation in vocal fold leukoplakia.Materials and methodsSeventy patients with vocal fold leukoplakia treated by CO2 or angiolytic laser (pulsed dye laser or potassium titanyl phosphate) were identified retrospectively. Data regarding patient characteristics, treatment details, treatment outcomes including disease control (recurrence and progression) and the Voice Handicap Index, GRBAS scale, and acoustics were evaluated. The mean follow-up duration after initial treatment was 32 ± 26 months.ResultsThe study group comprised 14 patients who underwent CO2 laser microflap excision and 56 who underwent angiolytic laser stripping. Of the patients treated with CO2 laser, 11 (79%) had no recurrence and three (21%) showed recurrent leukoplakia, of which one patient (7%) showed histologic grade progression. Of patients who underwent angiolytic laser stripping, 12 had disease recurrence (21%), among whom three (5%) showed disease progression. Laser surgery type, disease extent, and histologic grade showed no significant differences in recurrence or progression rates. The postoperative Voice Handicap Index significantly improved (P = .03) and the G score significantly decreased (P < .001) in the angiolytic laser treatment group. In contrast, the Voice Handicap Index increased postoperatively in the CO2 laser group (P = .046).ConclusionsThe long-term recurrence or progression rates were not significantly different between angiolytic and CO2 laser treatment. The angiolytic laser stripping group showed better voice preservation compared with the CO2 laser group. Angiolytic laser stripping is suggested as an effective treatment option for vocal fold leukoplakia with comparable disease control and better voice preservation.

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Phonatory outcome of 585nm/pulsed-dye laser in the management of glottic leukoplakia

Cited by 21 publications

References 17 publications

Treatment of Hemorrhagic Vocal Polyps by Pulsed Dye Laser-Assisted Laryngomicrosurgery

Treatment of Hemorrhagic Vocal Polyps by Pulsed Dye Laser-Assisted Laryngomicrosurgery

Treating Oral Leukoplakia with a 532-nm Pulsed Diode Laser

Angiolytic laser stripping versus CO2 laser microflap excision for vocal fold leukoplakia: Long-term disease control and voice outcomes

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