Phase behavior of aqueous mixtures of dodecyltrimethylammonium bromide (DTAB) and sodium dodecyl sulfate (SDS)

Herrington, Kathleen L.; Kaler, Eric W.; Miller, David D.; Zasadzinski, Joseph A.; Chiruvolu, S.

doi:10.1021/j100153a058

Cited by 363 publications

(408 citation statements)

References 9 publications

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“…Unlike steadystate fluorescence measurements taking advantage of conventional spectrophotometers, this method requires the application of single-photon counting equipment and analysis by appropriate non-linear fitting software. Utilisation of time-resolved fluorescence quenching resulted in the determination of micelle aggregation number of conventional surfactants such as DTAB [13,30], cetyltrimethylammonium bromide (CTAB) [31,32], SDS [16,33,34], sodium lauryl ether sulfate [35].…”

Section: Introductionmentioning

confidence: 99%

Determination of micelle aggregation numbers of alkyltrimethylammonium bromide and sodium dodecyl sulfate surfactants using time-resolved fluorescence quenching

2015

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Abstract:The time-resolved fluorescence quenching method was applied to determine the micelle aggregation number of cationic single-chain surfactants dodecyltrimethylammonium bromide (DTAB), cetyltrimethylammonium bromide (CTAB) and anionic surfactant sodium dodecyl sulfate (SDS). The concentration dependence of micelle aggregation number was found to be linear for all investigated surfactants in the concentration range 2-15 × the value of critical micelle concentration of the respective surfactant. The values of micelle aggregation number were found in the range 30-77. Different trends in the linear concentration dependence of micelle aggregation number were observed for cationic surfactants and for the anionic surfactant SDS. A small slope value was found for cationic surfactants, while the SDS micelle aggregation number concentration dependence showed significantly a larger slope value. The aggregation number increase with the increasing SDS concentration results in the micellar growth. Results from a simple analysis based on computer models of cationic and anionic surfactant molecules with dodecyl chains supports, the formation of intramicellar hydrogen bonding between surfactant molecules in SDS micelle shell.

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Section: Introductionmentioning

confidence: 99%

Determination of micelle aggregation numbers of alkyltrimethylammonium bromide and sodium dodecyl sulfate surfactants using time-resolved fluorescence quenching

2015

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“…9 On the other hand, catanionic vesicles have been shown to form spontaneously and reversibly and to remain stable for long periods of time, which strongly suggests that they are thermodynamically stable systems. Since the initial work by Hargreaves and Deamer 11 and Kaler and co-workers, 7,[12][13][14] several reports have been presented addressing vesiculation of catanionic mixtures. [15][16][17][18][19] Theoretical models accounting for the stability of these vesicles have also been proposed.…”

Section: Introductionmentioning

confidence: 99%

Vesicle Formation and General Phase Behavior in the Catanionic Mixture SDS−DDAB−Water. The Anionic-Rich Side

et al. 1998

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Catanionic mixtures are aqueous mixtures of oppositely charged surfactants which display novel phase behavior and interfacial properties in comparison with those of the individual surfactants. One phase behavior property is the ability of these systems to spontaneously form stable vesicles at high dilution. The phase behavior of the mixture sodium dodecyl sulfate (SDS) -didodecyldimethylammonium bromide (DDAB) in water has been studied in detail, and two regions of isotropic vesicular phases (anionic-rich and cationic-rich) were identified. Cryo-transmission electron microscopy allowed direct visualization of relatively small and polydisperse unilamellar vesicles on the SDS-rich side. Monitoring of the microstructure evolution from mixed micelles to vesicles as the surfactant mixing ratio is varied toward equimolarity was also obtained. Further information was provided by water self-diffusion measurements by pulsed field gradient spin-echo NMR. Water molecules can be in fast or slow exchange between the inside and outside of the vesicle with respect to the experimental time scale, depending on membrane permeability and vesicle size. For the SDSrich vesicles, a slow-diffusing component of very low molar fraction observed for the echo decays was traced down to very large vesicles in solution. Light microscopy confirmed the presence of vesicles of several microns in diameter. Thus, polydispersity seems to be an inherent feature of the system.

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“…A limited number of alternative procedures that do not use external energy sources, however, have been described. Particles formed from a spontaneous vesiculation process have been reported that use temperature jumps near the phospholipid phase transition (1)(2)(3), pH jumps (4-7), and admixtures of high surface tension surfactants (8)(9)(10)(11)(12)(13)(14)(15)(16)(17), which produce vesicles that are stable within a narrow regime of solution conditions. These methods are not used, however, to produce poly(n)ethylene oxide (PEO)-modified sterically stabilized liposomes with long circulation times in vivo (18) and other commercialized liposome formulations.…”

mentioning

confidence: 99%

Spontaneous liposome formation induced by grafted poly(ethylene oxide) layers: Theoretical prediction and experimental verification

Szleifer

Gerasimov

Thompson

1998

Proc. Natl. Acad. Sci. U.S.A.

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Spontaneous liposome formation is predicted in binary mixtures of f luid phase phospholipids and poly(n)ethylene oxide (PEO)-bearing lipids by using single chain mean field theory. The range of stability of the spontaneous liposomes is determined as a function of percentage of PEO-conjugated lipids and polymer molecular weight. These predictions were tested by using cast films of 1,2-diacylsn-glycerophosphocholines (e.g., egg L-␣-lecithin, 1,2-dimyristoyl-sn-glycero-3-phosphocholine, 1,2-dipalmitoyl-snglycero-3-phosphocholine, and 1,2-distearoyl-sn-glycero-3-phosphocholine) and 1,2-dipalmitoyl-sn-glycerophosphatidylethanolamine-PEO conjugates (i.e., 1,2-dipalmitoylsn-glycero-3-phosphoethanolamine-N-[methoxypoly(ethylene glycol)2000]carboxamide and 1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[methoxypoly(ethylene oxide)5000] carboxamide) that were hydrated above their gel-liquid crystal phase transition temperatures. Particle sizes of the resulting dispersions, analyzed by quasielastic light scattering, solute retention, 31 P NMR, and freeze-fracture electron microscopy measurements, confirmed the single chain mean field predictions. These data indicate that thermodynamically stable, unilamellar liposomes are formed spontaneously by simple hydration of f luid phase phospholipid bilayer films containing low molar ratios of PEO-based amphiphiles. They further suggest that the equilibrium size and colloidal properties of f luid phase, PEO-modified liposomes can be predicted by using this theoretical approach. The implication of these results on the design and processing of sterically stabilized liposomes used in drug delivery applications also is described.Since their discovery by Bangham in 1965, many processing methods for liposome production have been developed. The majority of these methods require the input of high energy (e.g., ultrasonic treatment, high pressure, and͞or elevated temperatures) to disperse low critical micelle concentration phospholipids as a metastable liposome phase. A limited number of alternative procedures that do not use external energy sources, however, have been described. Particles formed from a spontaneous vesiculation process have been reported that use temperature jumps near the phospholipid phase transition (1-3), pH jumps (4-7), and admixtures of high surface tension surfactants (8-17), which produce vesicles that are stable within a narrow regime of solution conditions. These methods are not used, however, to produce poly(n)ethylene oxide (PEO)-modified sterically stabilized liposomes with long circulation times in vivo (18) and other commercialized liposome formulations. Given the diverse nature of their applications in biotechnology and pharmacology, we sought a simple methodology for producing thermodynamically stable spontaneous liposomes, derived from commercially available phospholipids, that could survive in more challenging chemical environments. Our strategy for discovering these conditions focused on using a quantitative theoretical approach to analyze ho...

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Phase behavior of aqueous mixtures of dodecyltrimethylammonium bromide (DTAB) and sodium dodecyl sulfate (SDS)

Cited by 363 publications

References 9 publications

Determination of micelle aggregation numbers of alkyltrimethylammonium bromide and sodium dodecyl sulfate surfactants using time-resolved fluorescence quenching

Determination of micelle aggregation numbers of alkyltrimethylammonium bromide and sodium dodecyl sulfate surfactants using time-resolved fluorescence quenching

Vesicle Formation and General Phase Behavior in the Catanionic Mixture SDS−DDAB−Water. The Anionic-Rich Side

Spontaneous liposome formation induced by grafted poly(ethylene oxide) layers: Theoretical prediction and experimental verification

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