Pharyngocutaneous Fistula Following Total Laryngectomy: a High-Volume Tertiary Centre Series

Penêda, José Ferreira; Fernandes, João; Monteiro, Eurico

doi:10.1007/s13193-023-01765-1

Cited by 1 publication

(1 citation statement)

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“…Pharyngocutaneous fistula refers to a fistula formed during total laryngectomy, where the surgical incision cannot heal due to various reasons, and the pharyngeal cavity communicates with the skin of the neck 11 . The clinical manifestation of PCF is that saliva is stored in the subcutaneous or incision tissue, forming a purulent cavity that ruptures to the skin or incision edge, allowing the pharyngeal, oesophageal and skin to enter the sinus tract, and through this, saliva or food can overflow to the skin 12,13 . The formation of PCF may be due to the patient's underlying disease, or excessive excision of the pharyngeal mucosa during surgery, resulting in excessive tension during suturing; Either the tight suture leads to mucosal ischaemic necrosis or secondary infection, or the patient has poor wound healing ability after radiotherapy, or improper postoperative diet 14,15 .…”

Section: Methodsmentioning

confidence: 99%

Risk factors and healing factors for pharyngocutaneous fistula after total laryngectomy for laryngeal cancer: An epidemiological study

Tai,

Liu,

Liu

et al. 2024

International Wound Journal

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To analyse the risk factors and healing factors of pharyngocutaneous fistula (PCF) in patients with laryngeal cancer after total laryngectomy, and to explore the relevant epidemiology. A retrospective analysis was conducted on laryngeal cancer patients who underwent total laryngectomy in our hospital from January 2010 to December 2022. The 349 patients included in the study were divided into a PCF group of 79 and a non‐PCF group of 270. Perform one‐way analysis of variance and multivariate logistic analysis on various data of patients included in the statistics, and analyse the risk factors and healing factors of PCF. Smoking, history of radiation therapy for laryngeal cancer, history of chemotherapy for laryngeal cancer, tumour location (larynx, pharynx, oesophagus), preoperative albumin, postoperative proteinaemia, <99 haemoglobin, postoperative haemoglobin, postoperative C‐reactive protein (CRP) level are the risk factors for PCF. Also, radiation therapy and postoperative proteinaemia were the main reasons for preventing PCF healing. Smoking history, laryngeal cancer, radiation therapy, albumin, haemoglobin and CRP are risk factors for postoperative PCF after total laryngectomy, while radiation therapy and postoperative hypoalbuminaemia are key factors affecting PCF healing.

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Section: Methodsmentioning

confidence: 99%