“…In view of these observations, we assumed that some relationship would exist between the action of aldosterone and renal carbonic anhydrase. The relation between adrenocortical steroids and renal carbonic anhydrase was previously reported by several workers (Arima, 1959;Sugimoto, 1961;Holmgard, 1962), but detailed study has not been established. Previously we performed a series of experiments with mice and rats to elucidate this relationship in several organs (Suzuki and Ogawa, 1962, 1963aand b, and 1965.…”