1977
DOI: 10.3758/bf03337856
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Abstract: Dose-response relationships were established for the effect of d-and I-amphetamine on hoarding latency, the time course of hoarding, and the size of the total hoard. Both isomers displayed a marked effect on hoarding latency with the d isomer approximately twice as potent as the I form. The effects of the isomers on latency were reflected in the temporal profiles and in the sizes of the accumulated hoards. In a further experiment, pimozide-a dopamine blocking agent-drastically reduced the overall level of hoar… Show more

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Cited by 24 publications
(6 citation statements)
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“…Electrical stimulation and lesion studies have also implicated the anterior cingulate gyrus (24), the hypothalamus (25), the hippocampus, and the septum (26) in the mediation of food hoarding behavior in rodents. Food hoarding is also stimulated by dopamine agonists (27) but is reduced by lesions of dopaminergic pathways (28,29), as well as by administration of serotonin agonists (30). Gonadal steroids (31), benzodiazepines (32), and opiates (33) may also play roles in modulating hoarding behavior in animals.…”
Section: Resultsmentioning
confidence: 98%
“…Electrical stimulation and lesion studies have also implicated the anterior cingulate gyrus (24), the hypothalamus (25), the hippocampus, and the septum (26) in the mediation of food hoarding behavior in rodents. Food hoarding is also stimulated by dopamine agonists (27) but is reduced by lesions of dopaminergic pathways (28,29), as well as by administration of serotonin agonists (30). Gonadal steroids (31), benzodiazepines (32), and opiates (33) may also play roles in modulating hoarding behavior in animals.…”
Section: Resultsmentioning
confidence: 98%
“…The present findings suggest that dopamine in the mesolimbic system is necessary for the expression of hoarding behavior. In an earlier study which showed that the neuroleptic pimozide reduced hoarding, Blundell, Strupp, and Latham (1977) suggested a dopaminergic substrate for this behavior. The abolition of hoarding behavior by 6-OHDA nucleus accumbens lesions has been confirmed in parallel studies (Alpert & Iversen, 1982).…”
Section: Discussionmentioning
confidence: 99%
“…Although we are not aware of studies addressing the effects of QNP on hoarding, there is evidence that manipulation of the dopaminergic system affects this behavior. For instance, lesions of dopaminergic pathways or the administration of dopamine antagonists were found to reduce hoarding without affecting actual water or food intake (Blundell et al 1977;Kelley and Stinus 1985;Whishaw and Kornelsen 1993).…”
Section: Appetition Consumption and Motivationmentioning
confidence: 99%