Pharmacologic-Augmented Treatments

Pharmacological enhancement of extinction learning.

“…Animal studies have suggested important differences in fear extinction processes between young and mature animals (Kim & Richardson, 2010), and it is thought that these differences could lead to differences in DCS response (Byrne et al, 2014). However, the relatively limited DCS literature in youth samples has revealed results similar to those observed with adults regarding efficacy (Byrne et al, 2014;Schneider & Storch, 2019). Further research, however, is needed to explore age differences in DCS response.…”

“…Faster response to exposure may reduce treatment duration, cost, and premature patient dropout (Byrne et al, 2014); thus, even a modest speeding effect of DCS may be clinically useful. More studies, however, are needed to better understand the underlying mechanisms of DCS and to personalize its use to optimize effects (Schneider & Storch, 2019).…”