“…We and other investigators have previously published encouraging PK results by administrating the aminoglycoside before or at the beginning of the hemodialysis treatment. 5 - 7 These regimens have a higher probability of attaining PK/PD targets, such as peaks >8 mg/mL, while limiting exposure (area under the curve [AUC]). In this letter, we report our 2-year experience of administrating tobramycin in the first 30 minutes of the hemodialysis treatment among outpatients.…”