Pharmacist, general practitioner, and nurse perceptions, experiences, and knowledge of medication dosage form modification

Nguyen, Thi-My-Uyen; Lau, Esther; Steadman, Kathryn J.; Cichero, Julie A. Y.; Dingle, Kaeleen; Nissen, Lisa

doi:10.2147/iprp.s53797

Cited by 4 publications

(4 citation statements)

References 27 publications

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“…To fulfill this aim they should have excellent medication knowledge in all aspects of this subject. However, there is little research on pharmacists' experiences, and knowledge about oral dosage forms [24][25][26][27]. No research has directly focused on attitudes, knowledge and practice of pharmacists toward splitting or crushing OSDFs.…”

Section: Discussionmentioning

confidence: 99%

Knowledge, Attitudes, and Practices of Pharmacists Toward Splitting or Crush-ing Oral Solid Dosage Forms in Palestine: Safety and Therapeutic Implications

Zaid¹,

Abdallah²,

Zyoud³

2019

Palestinian Medical and Pharmaceutical Journal

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Tablet splitting and crushing is a widespread practice among health-care providers and patients for increasing dose flexibility, or making tablet parts easier to swallow, or allowing cost savings for medications. However, this practice may be dangerous because some formulations and classes of drugs are unsuitable for crushing or splitting and may cause significant problems, especially in drugs with low therapeutic indices. This study was conducted to examine the knowledge, attitudes and practice of pharmacists toward splitting or crushing oral solid dosage forms (OSDFs) in Palestine. This is a self-administered cross-sectional questionnaire survey involving 300pharmacistswho work at community pharmacists and hospitals in the West Bank area of Palestine and was conducted during the period May 2013 to August 2013. Data were collected using a pretested questionnaire consisting of four sections and analyzed using descriptive statistics and correlation. A total of 325 questionnaires were distributed and 300 were completed. About 67.3% of the pharmacists had good knowledge. Nearly 69% of the pharmacists had a good attitude. There was a positive correlation (p=0.002, r=0.18) between knowledge and attitude scores among pharmacists. Approximately 83.7% of the pharmacists had good practices. There was a significant difference between practice and non-practice respondents regarding knowledge score (p=0.037). This study has identified knowledge, attitude and practice gaps among health-care practitioners, especially among pharmacists. Therefore, improving appropriate knowledge regarding splitting and crushing OSDFs is required by planning and developing programs for local health education purposes. KEYWORDS: Splitting tablets; Pharmacists; Oral Solid Dosage Forms; Crushed drugs. BACKGROUNDOne of the significant current discussions from a medical and legal point of view is splitting or crushing oral solid dosage forms (OSDFs). Splitting OSDFs refers to the practice of dividing a tablet to provide a lower dose of the active ingredient or to obtain multiple smaller doses for many purposes. While crushing tablet refers to the process of converting tablets into powder by using suitable pharmacy tools such as mortar and pestle. These may provide several advantages. Patients usually split tablets for various reasons, such as: (i) providing the patient with the desired dose when the product is not available at the required strength, e.g. hydrochlorothiazide: the available dose is 25mg and the drug is commonly used in doses of 12.5mg, thus the patient needs to split the tablet to receive the smaller dose. Another example is converting atenolol tab-12 ‫ـــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــ‬ ‫ـ‬ ‫ـــــــ‬ ‫ـ‬ ‫ـــــــــــــــــ‬ "Knowledge, Attitudes, and Practices of Pharmacists Toward Splitting or ……"

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Section: Discussionmentioning

confidence: 99%

Knowledge, Attitudes, and Practices of Pharmacists Toward Splitting or Crush-ing Oral Solid Dosage Forms in Palestine: Safety and Therapeutic Implications

Zaid¹,

Abdallah²,

Zyoud³

2019

Palestinian Medical and Pharmaceutical Journal

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“…The role of the pharmacists in patient-centered medical home practices revealed knowledge and skills that can complement the care provided by other health care team members [52]. Moreover, many studies emphasize that the cooperation between general practitioners, pharmacists, and nurses is necessary to effectively dispense drugs to the patient [53]. A very interesting report concerning approaches in improving the outcome of the patient and health care system through advanced pharmaceutical experience and have recently been reviewed by Giberson et al [54].…”

Section: Pharmacistsmentioning

confidence: 99%

“…They conducted the survey among representatives of these three professions. It turned out that the personnel working in the public health centers employing specialists in various fields, for example hospitals often cooperate with each other discussing and exchanging views and experiences [6,53].…”

Section: Pharmacistsmentioning

confidence: 99%

Nurses and Pharmacists in Interdisciplinary Team of Health Care Providers in Photodynamic Therapy

Kocki¹,

Czarczyńska-Goślińska²,

Kocka³

et al. 2017

Photomedicine - Advances in Clinical Practice

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Background: The modern treatment is based on wide cooperation between diverse representatives of medical professions. The photodynamic therapy is a noninvasive method of treatment both neoplastic diseases and miscellaneous noncancerous illnesses. It is complementary and competitive in some way to various traditional treatment techniques, including chemotherapy, radiotherapy, and surgery. This review emphasizes the significance of collaboration between specialists engaged in research, development, and practical use of photodynamic therapy.Methods: A literature search of electronic bibliographic databases and scientific publishers was performed. The relevant literature was analyzed to identify articles on the involvement of nurses, pharmacists, physicians, and other representatives in photodynamic therapy treatment.Results: In the photodynamic therapy, the overall success is not only dependent of a single unit. Coordinated actions of representatives possessing expertise in various fields of medical, and natural sciences are necessary both during joint research, development, and during the course of the photodynamic therapy treatment in clinics. Conclusions:The effective interaction between professionals and the division of responsibilities at different stages of therapy can guarantee the successful treatment. During therapy, the most important role belongs to the patient who is responsible for acting in accordance with schedules elaborated by physicians, nurses, and pharmacists.

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“…chewable tablets, effervescent and dispersible) may be used safely when available (Dejaeger, 2008; Lau et al., 2018; Salmeron, 2018; Wright et al., 2020). The SODF necessity can be assessed, and deprescription performed, including a safe therapeutic alternative can be found (Mc Gillicuddy et al., 2016; Nguyen et al., 2014).…”

Section: Introductionmentioning

confidence: 99%

Optimization of solid oral dosage form administration to patients with swallowing difficulties: An integrative review

Ferreira‐Neto,

de Lara,

Cominato

et al. 2023

Journal of Advanced Nursing

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AimTo appraise and synthesize research investigating optimizing the administration of solid oral dosage forms (SODFs) to adults with swallowing difficulties.DesignAn integrative review.MethodsAn electronic search was conducted on Medical Literature Analysis and Retrieval System Online (Public Medline interface), Elsevier SciVerse Scopus and Scientific Electronic Library Online (updated February 2023). Restriction regarding the publication date was not considered for the inclusion of records. Studies addressing risks, general aspects, recommendations about patient postural adjustments, swallowing techniques, swallowing aids and aspects of concealment of SODFs were included.ResultsFifty‐three records published between 2002 and 2021 were included. The main administration risks were aspiration, asphyxia and solid oral dosage form‐induced oral/oesophageal mucosal lesions. The most frequent general aspect reported was administering one oral dosage form at a time. The sitting position was the most patient postural adjustment mentioned. The most frequently reported solid oral dosage form swallowing technique was the lean‐forward method for capsules. Solid oral dosage form swallowing aids cited: tongue and throat lubricant and solid oral dosage form coating device, swallowing cup and swallowing straw.ConclusionThe literature data on administering SODFs for adults with swallowing difficulties were appraised and synthesized. Some aspects, for example, not administering SODFs simultaneously, can make swallowing safer. Postural adjustments and solid oral dosage form swallowing aids are important to avoid administration risks. Swallowing SODFs can be easier if learned by techniques. Liquid and food are helpful as vehicles, and several of these have been listed.Implications for the Profession and/or Patient CareBy optimizing the contributing factors of administering oral pharmacotherapy, the nurse can use appropriate practices to improve patient safety. Additionally, knowing and establishing the administration aspects are reasonable steps for standardizing care for patients with swallowing oral dosage form difficulties.Impact This study addressed administering SODFs to adult patients with swallowing difficulties. The administration of SODFs to adult patients with swallowing difficulties can be optimized if only one oral dosage form at a time is administrated and if patient postural adjustments, swallowing techniques and swallowing aids are used. This investigation will impact the care of patients with swallowing difficulties. Reporting MethodThe authors declare they adhered to the relevant EQUATOR guidelines and report following the Preferred Reporting Items for Systematic Reviews and Meta‐Analyses (PRISMA) 2020 Statement.Patient or Public ContributionNo patient or public contribution.

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Pharmacist, general practitioner, and nurse perceptions, experiences, and knowledge of medication dosage form modification

Cited by 4 publications

References 27 publications

Knowledge, Attitudes, and Practices of Pharmacists Toward Splitting or Crush-ing Oral Solid Dosage Forms in Palestine: Safety and Therapeutic Implications

Knowledge, Attitudes, and Practices of Pharmacists Toward Splitting or Crush-ing Oral Solid Dosage Forms in Palestine: Safety and Therapeutic Implications

Nurses and Pharmacists in Interdisciplinary Team of Health Care Providers in Photodynamic Therapy

Optimization of solid oral dosage form administration to patients with swallowing difficulties: An integrative review

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