Pharmaceuticals and related drugs

Abstract

This review surveys analytical methodology and subjects related to pharmaceutical analysis that appeared in Chemical Abstracts (CA) or Analytical Abstracts (AA) during the period between June 1974 and June 1976. The authors were selective and attempted to cite only those references that appeared to be significant and appeared in easily accessible journals. It is not as encompassing as the previous Pharmaceutical Review in 1975.The bibliography is divided into nine sections with separate numbering of each. The sections are Alkaloids (A), Antibiotics (B), Inorganic and Metal Containing Compounds (I), Sulfur Containing Compounds (S), Nitrogen and Oxygen Containing Compounds (N), Steroids (R), Vitamins (V), Formulations and Mixture (F), and New Techniques (T).

Indirect spectrophotometric determination of benzylpenicillin and cloxacillin in pharmaceutical preparations

“…Various analytical methods have been reported, which involve general determination without discriminating between individual penicillins [1][2][3][4][5]. Such methods, for instance, involve spectrophotometry using reagents such as chloranil [6], ferroin [7], ammonium molybdate [8], ninhydrin in 0.2 M citrate buffer (pH 5) containing SnC12 [9], chloranilic acid in dioxane and dioxane-DMF [10], ammonium vanadate [11,12] and copper(II) acetate [13].…”

Stability assays of aged pharmaceutical formulas for thiamine and pyridoxine by high performance thin-layer chromatography and derivative ultraviolet spectrometry

“…On the other hand, relative to other analytical techniques applied to vitamin analysis (1)(2)(3)(10)(11)(12)(13)(14), UV absorption spectrometry stands out as to frequency of use and availability in many analytical laboratories. Thus, the individual UV absorption characteristics of thiamine and pyridoxine are well known (2, 15), both of them showing excellent absorbance characteristics at 200-400 nm.…”