Pharmaceutical packaging: recent trends and challenges

Sah, Sunil Kumar; Kaity, Santanu

doi:10.1016/b978-0-323-91817-6.00009-7

Cited by 1 publication

(1 citation statement)

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“…In recent years, there has been a growing emphasis on sustainability within the healthcare sector, driven by environmental concerns [ 2 ]. Furthermore, there is a rising demand for safeguarding against physical damage and external contaminants, which can prevent the entry of moisture and oxygen while preserving packaged healthcare materials [ 3 ]. Epoxy resins are now finding new applications due to their outstanding performance and unique characteristics, such as high mechanical strength and chemical resistance [ 4 ].…”

Section: Introductionmentioning

confidence: 99%

Development of Halloysite Nanotube-Infused Thermoset Soybean Bio-Resin for Advanced Medical Packaging

Saedi,

Sobhan,

Hoff

et al. 2024

Polymers

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The development of eco-friendly, mechanically stable, and biocompatible materials for medical packaging has gained significant attention in recent years. Halloysite nanotubes (HNTs) have emerged as a promising nanomaterial due to their unique tubular structure, high aspect ratio, and biocompatibility. We aim to develop a novel soybean oil-based thermoset bio-resin incorporating HNTs and to characterize its physical and functional properties for medical packaging. Soybean oil was epoxidized using an eco-friendly method and used as a precursor for preparing the thermoset resin (ESOR). Different amounts of HNTs (0.25, 0.50, and 1.0 wt.%) were used to prepare the ESOR/HNTs blends. Various characteristics such as transparency, tensile strength, thermal resistance, and water absorption were investigated. While incorporating HNTs improved the tensile strength and thermal properties of the ESOR, it noticeably reduced its transparency at the 1.0 wt.% level. Therefore, HNTs were modified using sodium hydroxide and (3-Aminopropyl) triethoxysilane (APTES) and ESOR/HNTs blends were made using 1.0 wt.% of modified HNTs. It was shown that modifying HNTs using NaOH improved the transparency and mechanical properties of prepared blends compared to those with the same amount of unmodified HNTs. However, modifying using (3-Aminopropyl) triethoxysilane (APTES) decreased the transparency but improved the water absorption of prepared resins. This study provides valuable insights into the design of HNT-based ESOR blends as a sustainable material for medical packaging, contributing to the advancement of eco-friendly packaging solutions in the healthcare industry.

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Section: Introductionmentioning

confidence: 99%