Pharmaceutical and Analytical Standardization of “Medopachak Vati”

Abstract

In ancient Ayurvedic classics, many formulations are there like herbal, mineral and herbomineral in origin. These formulations are effective in many diseases depending upon their qualities and properties. In this study, we are dealing with medopachak vati which is herbal preparation. In Charak Samhita, Uttarsthana, Aacharya Charak mentioned Pachak Yoga in the treatment of Vishamjwara. “Medopachak yoga” which is useful in the Treatment of Medogatjwar. Many of the Ayurvedic paractitioners prescribe Medopachak yoga in various dosage forms like kashaya (Decoction), Churna (Powder) as per their convenience. Dosage form for administration plays an important role in the reaction and delivery of particular drug on a specific system. Tablets are easy to prepare, packing, transportation and administration to patients. Hence tablet form is the most accepted dosage form amongst all. In this study, formulation of “Medopachak Yoga” is transformed to the tablet form by using modern equipments and analytical techniques. An effort is made to validate the pharmaceutical and analytical procedures to maintain the quality of product and to avoid batch to batch variation. Pharmacopeial standards are set for this Ayurvedic formulation in tablet form. All the 3 samples were prepared by this method show identical characteristics and analytical parameters do not show much significant difference. These set parameters may be used for the further pharmaceutical preparations.

Role of Ayurveda in Delayed Speech in Children –A Case Series

“…The Ayurvedic Treatment consisted of the following combinations of Herbo-mineral formulations such as -Krumimudgar rasa 5,6 and the herbal combination of -Kiratatikta 7 (Swertia chirata), Guduchi 8 (Tinospora cordifolia), Chandan 9 (Santalum album), and Shunthi 10 (Zinziber officinalis). 11 They were mixed with honey and administered for 4 weeks. Theoretical Action for Therapeutic Intervention action: The abovesaid formulations are effective in eradicating the environment that is favorable for worms, which is marked by Kapha and Kleda accumulation.…”

Need of Standardization of Ayurveda Formulations

“…Ancient times the medicine preparation was carried out under the supervision of Vaidyas and they have developed some protocols for collection and storage of raw materials and manufacturing of medicines. They had developed guidelines based on the following factors: [3] 1. Place of origin and time of collection of raw material 2.…”

“…Substitute is those drugs/materials having more or less similar medicinal properties of that of genuine one. [5] It is done due to non-availability of drugs, controversy of drug identity, confusion in nomenclature of different plants having similar name, regional availability, seasonal availability, shelf life, cost, similar Rasapancaka and morphological resemblance. Nowadays the concept of substitution is entirely converted into intentional and unintentional malpractices of adulteration.…”