Personalized metabolic profile estimations using oral glucose tolerance tests

Lee, Young Boum; Lee, Jeong Hoon; Park, Eun Seok; Kim, Ga Yul; Leem, Chae Hun

doi:10.1016/j.pbiomolbio.2014.08.011

Cited by 5 publications

(1 citation statement)

References 33 publications

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“…An OGTT was performed according to the standard protocol and as described previously [20]. In brief, participants fasted for at least 12 hours before the experiment and were asked to consume 75 g glucose (Glu-orange; McNulty Pharmaceutical, Seoul, Korea).…”

Section: Methodsmentioning

confidence: 99%

Relationship of the Cold‐Heat Sensation of the Limbs and Abdomen with Physiological Biomarkers

Pham

Lee

Ga‐Yul

et al. 2016

Evidence-Based Complementary and Alternative Medicine

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The present study explored the relationship between the regional Cold-Heat sensation, the key indicator of the Cold-Heat patterns in traditional East Asian medicine (TEAM), and various biomarkers in Korean population. 734 apparently healthy volunteers aged 20 years and older were enrolled. Three scale self-report questions on the general thermal feel in hands, legs, and abdomen were examined. We found that 65% of women tended to perceive their body, particularly their hands and legs, to be cold, versus 25% of men. Energy expenditure and temperature load at resting state were lower in women, independently of body mass index (BMI). Those with warm hands and warm legs had a 0.74 and 0.52 kg/m2 higher BMI than those with cold hands and cold legs, respectively, regardless of age, gender, and body weight. Norepinephrine was higher, whereas the dynamic changes in glucose and insulin during an oral glucose tolerance test were lower in those with cold extremities, particularly hands. No consistent differences in biomarkers were found for the abdominal dimension. These results suggest that gender, BMI, the sympathetic nervous system, and glucose metabolism are potential determinants of the Cold-Heat sensation in the hands and legs, but not the abdomen.

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Section: Methodsmentioning

confidence: 99%