Personalized Medicine: Integrating Individual Exposure and Response Information at the Bedside

Mould, Diane R.; Lesko, Lawrence J.

doi:10.1007/978-1-4939-1304-6_2

Cited by 2 publications

(1 citation statement)

References 35 publications

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“…One recent paper 76 describes emerging roles of clinical PMx in cancer precision medicine and provides a roadmap for future precision oncology with challenges and opportunities for interdisciplinary collaboration. Another useful idea for precision medicine is a dashboard system that integrates real‐time patient monitoring and calculation of optimal dose and timing of dose delivery 77 . An example of a dashboard system is a fully automated artificial pancreas system for patients with type 1 diabetes 78 .…”

Section: Integration Of Fieldsmentioning

confidence: 99%

Pharmacometrics meets statistics—A synergy for modern drug development

Ryeznik

Sverdlov

Svensson

et al. 2021

CPT Pharmacom & Syst Pharma

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Modern drug development problems are very complex and require integration of various scientific fields. Traditionally, statistical methods have been the primary tool for design and analysis of clinical trials. Increasingly, pharmacometric approaches using physiology‐based drug and disease models are applied in this context. In this paper, we show that statistics and pharmacometrics have more in common than what keeps them apart, and collectively, the synergy from these two quantitative disciplines can provide greater advances in clinical research and development, resulting in novel and more effective medicines to patients with medical need.

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Section: Integration Of Fieldsmentioning

confidence: 99%