Peritoneal carcinomatosis secondary to carcinoid tumour

Abstract

Carcinoid tumours are neuroendocrine neoplasms that can appear in every location of the digestive tract. They are low aggressive tumours, although they often produce local invasion and hepatic metastases, whose resection allows long-term survival. We report a case of a 64-year-old man with ileal carcinoid tumour, that underwent ileal resection and metastasectomy of one lesion in liver segment II. Surgical findings indicated peritoneal carcinomatosis. Carcinoid dissemination as peritoneal carcinomatosis has been rarely described in the literature. Cytoreductive surgery, always when complete resection is aimed, achieves asymptomatic long-term survivals.

ENETS Consensus Guidelines for the Management of Peritoneal Carcinomatosis from Neuroendocrine Tumors

“…PC from GEP tumors seems to have two particularities: (1) it is more frequently associated with large (nongastrinomas) pancreaticoduodenal GEP tumors or GEP tumors of midgut origin (carcinoids) and (2) PC infrequently is an isolated event [2,3,4]. Lymph nodes are present in most of the patients at the time of diagnosis and 30–80% of patients present with synchronous PC and liver metastases [2,3,4].…”

“…Lymph nodes are present in most of the patients at the time of diagnosis and 30–80% of patients present with synchronous PC and liver metastases [2,3,4]. The two series of patients with PC from GEP tumors were published in 1996 (n = 11) and 2005 (n = 37), reporting a total number of 48 patients [2,4].…”