Peritoneal Adhesions: Causes and Prevention

Sm, Almdahl; Burhol, P. G.

doi:10.1159/000171238

Cited by 7 publications

(2 citation statements)

References 23 publications

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“…Postsurgical adhesions occur in 67-93% of abdominal surgical patients and are a primary cause of postoperative small bowel obstruction [11,12]. Precipitating factors for adhesion formation are peritoneal injury, foreign body reaction, inflammation, and tissue ischemia [13][14][15]. The development of a physiological material to cover peritoneal defects is very desirable.…”

Section: Introductionmentioning

confidence: 99%

Construction of a Transplantable Tissue-Engineered Artificial Peritoneum

Kuga¹,

Morisaki²,

Nakamura³

et al. 2004

Eur Surg Res

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Background: Peritoneal defects lead to serious postoperative problems. Thus the development of physiological material to cover peritoneal defects is very desirable. Aim: The aim of this study was to develop a transplantable artificial peritoneum. Method: The artificial peritoneum consisted of collagen gel, fibroblasts, and mesothelial cells, and histological features were analyzed. The artificial peritoneum at the site of a peritoneal defect in the rat was transplanted to the abdominal wall. Results: Histological examination revealed that the artificial peritoneum consisted of a flat mesothelial monolayer upon a stromal matrix. All transplanted artificial peritoneums adapted well to the host and prevented severe adhesion. Conclusion: Our artificial peritoneum may be a useful transplantable bioengineered material for repair of surgical peritoneal defects.

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Section: Introductionmentioning

confidence: 99%

Construction of a Transplantable Tissue-Engineered Artificial Peritoneum

Kuga¹,

Morisaki²,

Nakamura³

et al. 2004

Eur Surg Res

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“…Prevention and control of adhesion forma tion is an important clinical problem and scientific sub ject [1][2][3]. Treatment for lesions of the peritoneal serosa has always been a subject of controversy for abdominal surgeons.…”

Section: Introductionmentioning

confidence: 99%

Adhesion Response to Different Forms of Treating a Peritoneal Lesion: An Experimental Study in Rats

Egea¹,

Albasini²,

Carmona³

et al. 1995

Dig Surg

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The authors analyze the adhesion-forming capacity of various forms of treating a peritoneal lesion. There were four groups each of 10 rats, all receiving the same peritoneal lesion. The control group did not receive any treatment for this injury; in the remaining three, the peritoneal lesion was treated with electrocoagulation, stapling or interrupted suture. The animals were killed after 30 days and adhesions quantified according to a specially designed score which assessed the number of adhesions, their site, vascularization, thickness and tenacity. Electrocoagulation significantly generated the smallest number of adhesions. The application of stapling or suture stimulated the formation of adhesions to a larger extent, manual suture more so than the stapling.

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Prevalence of Adhesions and the Associated Costs in General Surgery

Lange¹,

Jeekel²

2000

Peritoneal Surgery

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Peritoneal Adhesions: Causes and Prevention

Cited by 7 publications

References 23 publications

Construction of a Transplantable Tissue-Engineered Artificial Peritoneum

Construction of a Transplantable Tissue-Engineered Artificial Peritoneum

Adhesion Response to Different Forms of Treating a Peritoneal Lesion: An Experimental Study in Rats

Prevalence of Adhesions and the Associated Costs in General Surgery

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