2016
DOI: 10.5935/1806-0013.20160044 View full text |Buy / Rent full text
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Abstract: BACKGROUND AND OBJECTIVES:Central sensitization is an important phenomenon for pain chronicity and is present in neuropathic pain. This study aimed at addressing some pathophysiological aspects of this phenomenon. CONTENTS: Some extra and intracellular aspects responsible for central sensitization genesis, especially phenotypic changes in plasticity of neurons involved in the process are described. CONCLUSION: Pain chronicity may result from changes in central nervous system neurons properties by the central s… Show more

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