Peripapillary RNFL Thickness Changes Evaluated with Spectral Domain Optical Coherence Tomography after Uncomplicated Macular Surgery for Epiretinal Membrane

Abstract

The selective decrease in the temporal and inferior p-RNFL thickness after vitrectomy for ERM removal could indicate inner retinal damage related to ILM peeling.

A study analyzing macular microvasculature features after vitrectomy using OCT angiography in patients with idiopathic macular epiretinal membrane

“…In the past, a large number of studies [18][19][20][21] have focused on the changes in microstructure of fovea due to iERM in order to identify the anatomic changes associated with the vision recovery after surgery. This included the integrity of ellipsoid zone, the central macular thickness (CMT) and the photoreceptor outer segments.…”

Longitudinal Changes in Retinal Nerve Fiber Layer Thickness Evaluated Using Avanti Rtvue-XR Optical Coherence Tomography after 23G Vitrectomy for Epiretinal Membrane in Patients with Open-Angle Glaucoma

“…After analyzing our results, we have found that there is a statistically significant increase in the RNFL thickness in the first month after temporal quadrant surgery ( Figure 2 ). It is probably associated with edema of the nerve fibers because of the axonal transport disorder leading to apoptosis and atrophy of the ganglion cells [ 7 , 16 , 17 ], which leads to the subsequent RNFL thinning 6 months after the procedure. Another explanation of this mechanism may be dehydration caused by the fluid to air exchange during PPV, toxic retinal damage with gas endotamponade, and mechanical damage during the removal of the vitreous body [ 7 , 16 , 17 ].…”

“…It is probably associated with edema of the nerve fibers because of the axonal transport disorder leading to apoptosis and atrophy of the ganglion cells [ 7 , 16 , 17 ], which leads to the subsequent RNFL thinning 6 months after the procedure. Another explanation of this mechanism may be dehydration caused by the fluid to air exchange during PPV, toxic retinal damage with gas endotamponade, and mechanical damage during the removal of the vitreous body [ 7 , 16 , 17 ]. Like Gharbiya et al [ 16 ], we did not notice any differences in the RNFL thickness between patients who underwent phacovitrectomy and those who underwent vitrectomy alone.…”

“…Another explanation of this mechanism may be dehydration caused by the fluid to air exchange during PPV, toxic retinal damage with gas endotamponade, and mechanical damage during the removal of the vitreous body [ 7 , 16 , 17 ]. Like Gharbiya et al [ 16 ], we did not notice any differences in the RNFL thickness between patients who underwent phacovitrectomy and those who underwent vitrectomy alone. Although our analysis was related to glaucoma patients and controls, we did not observe statistically significant changes in the total RNFL thickness in the upper and lower quadrants in both the groups.…”

The Role of Vitrectomy in Threatment of Epimacular Fibrosis

“…Статистически достоверное истончение слоя нерв-ных волокон сетчатки в обеих группах затронуло лишь темпоральный сектор (RNFL-T), что полностью соответ-ствует описанному в литературе представлению о наи-большей восприимчивости данного сектора [14,18,19].…”