2018
DOI: 10.1097/iae.0000000000001907
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Abstract: Peripapillary pachychoroid syndrome is a distinct PDS variant, in which peripapillary choroidal thickening is associated with nasal macular intraretinal and/or subretinal fluid and occasional disk edema. Recognition of PPS is important to distinguish it from disorders with overlapping features such as posterior uveitis and neuro-ophthalmologic conditions.

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Cited by 107 publications
(112 citation statements)
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References 28 publications
(35 reference statements)
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“…Increased choroidal thickness is thought to result predominantly from dilatation of choroidal vessels in Haller's layer. Increased diameter of choroidal vessels has been observed as larger hyporeflective lumen in cross-sectional OCT in eyes with CSC, PCV, focal choroidal excavation (FCE), and PPS [22,23]. In histological sections in eyes with PCV, dilated choroidal vessels with diameter of up to 300 µm have been observed.…”
Section: Pachyvesselsmentioning
confidence: 97%
See 1 more Smart Citation
“…Increased choroidal thickness is thought to result predominantly from dilatation of choroidal vessels in Haller's layer. Increased diameter of choroidal vessels has been observed as larger hyporeflective lumen in cross-sectional OCT in eyes with CSC, PCV, focal choroidal excavation (FCE), and PPS [22,23]. In histological sections in eyes with PCV, dilated choroidal vessels with diameter of up to 300 µm have been observed.…”
Section: Pachyvesselsmentioning
confidence: 97%
“…Peripapillary pachychoroid syndrome was recently described by Phasukkijwatana and colleagues as distinct variant of the pachychoroid disease spectrum in which maximal choroidal thickness occurs close to the optic nerve rather than subfovealy [23]. These patients typically present with nasal macular intraretinal and/or SRF and occasional optic nerve edema.…”
Section: Peripapillary Pachychoroid Syndromementioning
confidence: 99%
“…Based on multimodal imaging studies, pachychoroid has been postulated to be associated with increased hydrostatic pressure in the choroid causing disruption of Bruch's membrane, RPE dysfunction, and inner choroidal ischemia [8], and has been considered an underlying cause of a disease spectrum that includes pachychoroid pigment epitheliopathy, central serous chorioretinopathy, and pachychoroid neovasculopathy (type 1 neovascularization associated with shallow irregular RPE detachment with or without polyps). It is likely that pachychoroid is also associated with focal choroidal excavation [9], geographic atrophy (pachychoroid geographic atrophy [10]), peripapillary exudative changes (peripapillary retinoschisis [11] and peripapillary pachychoroid syndrome [12]) and drusen with a peculiar shape (pachydrusen [13]), although there is some debate as to whether pachychoroid is a primary cause of these conditions.…”
Section: Pachychoroid and Pcvmentioning
confidence: 99%
“…Pathologically dilated vessels in Haller's layer (pachyvessels) with overlying choriocapillaris attenuation are an essential feature required to define pachychoroid . This feature was originally described in the first article that introduced pachychoroid and has consistently been described in subsequent articles on pachychoroid disorders . Since it is a pathognomonic finding that defines the condition, it is considered to be related to the pathogenic mechanism of the diseases.…”
Section: Introductionmentioning
confidence: 99%
“…1,2 This feature was originally described in the first article that introduced pachychoroid and has consistently been described in subsequent articles on pachychoroid disorders. [3][4][5] Since it is a pathognomonic finding that defines the condition, it is considered to be related to the pathogenic mechanism of the diseases.…”
mentioning
confidence: 99%