Periosteal osteoblastoma: report of a case with a rare histopathologic presentation and review of the literature

Mortazavi, Seyed Mohammad Javad; Wenger, Doris E.; Asadollahi, Saeed; Torbaghan, Shams Shariat; Unni, K. Krishnan; Saberi, Sadegh

doi:10.1007/s00256-006-0169-2

Cited by 14 publications

(17 citation statements)

References 24 publications

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“…[6] Sometimes cartilage is seen. [7] In the present case secondary ABC like areas and cartilage was seen which is uncommon. The tumor does not permeate into the adjacent bony trabaculae and the mitotic activity is low.…”

Section: Case Reportsupporting

confidence: 43%

Osteoblastoma of Patella : A Rare Case

S¹,

Uma²,

Pramila³

et al. 2015

jemds

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Benign osteoblastoma of patella is a rare tumor. Majority of the tumors occur in spine, femur and tibia. Osteoblastoma presents as a diagnostic dilemma due to clinical similarity with other benign bone forming tumors. Histopathological examination is the main stay for diagnosis and has good prognosis. KEYWORDS: Osteoblastoma, patella, rare. CASE REPORT:A 16 year old boy from Srikakulam district presented to the outpatient department of orthopedics in the year 2012 with a six year history of knee pain and swelling of the left knee gradually increasing in size. The pain was worst at night. Six years back before the present swelling the boy had taken treatment for injury of left knee which healed after therapy. (Fig. 1) On physical examination the patella was painful with significant swelling compared to the contralateral side. Articular range of motion was normal. Haemogram, CRP, and ESR were completely normal. Standard lateral and AP view of X-ray patella showed a well circumscribed lesion of 5x3x3 cm size with mixed echogenicity. Both radiopaque and radio lucent areas rimmed by sclerotic margins. (Fig. 2) CT scan of the left knee confirmed the presence of fluid filled multi septate cavities suggesting the diagnosis of aneurysmal bone cyst / hemangioma. FNAC was performed and the aspiration showed only blood and blood cellular elements.Patellectomy was done with widely excised margins and the specimen was sent for histopathological examination. On gross examination the specimen measured 5x5x4 cms and cut section showed red granular surface with cystic spaces and tan white areas. It was gritty to cut and rimmed by sclerotic bone. (Fig. 3) On microcopy multiple sections showed anastamosing bony trabeculae irregularly arranged in a loose fibro vascular stroma. The trabeculae were lined by rim of osteoblasts which were polygonal in shape with moderate eosinophilic cytoplasm, round to oval nuclei and single nucleoli. Osteoid was seen. (Fig. 4) In addition there were large dilated vascular channels which had septae. In the septae there was loosely arranged spindle cells, osteoclastic giant cells, areas of hemorrhage and hemosiderin laden macrophages with adjacent foci of mature cartilage. (Fig. 5, 6). The diagnosis offered was Osteoblastoma with secondary ABC changes.The pain was completely relieved and the patient commenced normal exercise 48 hours after the operation. After 18 months, the follow up X-ray showed completely healed bone. On follow up further, the patient is fine till date without pain and recurrence of the lesion. DISCUSSION: Osteoblastoma is a rare benign tumor that accounts for less than 1% of all primary bone neoplasms. The neoplasm may be intramedullary, cortical, or sub periosteal in location. Sixty to sixty-five percent of the osteoblastomas are cortical and the remainder is medullary. [1] Osteoblastoma is usually diagnosed in young adults in the 2 nd to 4 th decade of life and males are affected approximately twice as frequently as females. [2]

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Section: Case Reportsupporting

confidence: 43%

Osteoblastoma of Patella : A Rare Case

S¹,

Uma²,

Pramila³

et al. 2015

jemds

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“…Osteoblastoma is a rare osteoblastic benign bone tumor that most frequently affects the vertebral column and sacrum, but it may virtually affect any bone in the body (1, 2). Several studies demonstrate 34% long tubular bone involvement and 30% vertebral bone involvement.…”

Section: Discussionmentioning

confidence: 99%

“…Its peak incidence is in the second decade, and it is rare before 10 years and after 30 years of age (1). For many years osteoblastoma was named as giant osteoid osteoma denoting its histopathological similarity with osteoid osteoma but it reveals a larger nidus (2, 3). Lesions with a nidus size more than 2 cm are considered as osteoblastoma (1-4).…”

Section: Introductionmentioning

confidence: 99%

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A Rare Case of Rib Osteoblastoma: Imaging Features and Review of Literature

2013

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Osteoblastoma is a rare benign, but locally aggressive bone tumor with rare malignant transformation. It mostly affects the vertebral column and long bones. Radiographically, it is seen as an expansile, oval, sclerotic or lytic mass-like lesion with well-defined borders, although sometimes it may mimic a malignant tumor such as osteogenic sarcoma by its irregular borders. Herein, we report a case of osteoblastoma in a 22 year-old man with a long history of back and neck pain accompanied with neck stiffness. On the routine chest X-ray, the salient lesion appeared as an expansile, oval, sclerotic mass with well-defined borders and speckled calcification without any internal lucency and periosteal reaction, involving the posterolateral aspect of the first left thoracic rib, a rare anatomical site. Despite the unusual location, osteoblastoma should be considered in the differential diagnosis of a solitary rib lesion.

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“…For example, one study of osteosarcoma of the mandible indicated that the use of chemotherapy was not a predictor for overall survival in a multivariate analysis [13]. More importantly, parosteal or periosteal osteogenic sarcomas, typically arising from the surface of bones, often times is a low-grade lesion, and the one situation in which chemotherapy is not routinely offered [2,14].…”

Section: Prognostic Factorsmentioning

confidence: 99%

Pediatric sarcomas occurring in adults

Maki

2008

Journal of Surgical Oncology

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Sarcomas arise in any part of the body, in any age group. Some sarcomas have a particular predilection for the pediatric population, and often bear specific chromosomal translocations. These "pediatric" sarcomas still occur in adults, often times with higher risk of dying of disease compared to children with a comparable diagnosis. The management of some of these rare tumors is discussed herein, including osteogenic sarcoma, Ewing sarcoma, and rhabdomyosarcoma.

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Periosteal osteoblastoma: report of a case with a rare histopathologic presentation and review of the literature

Cited by 14 publications

References 24 publications

Osteoblastoma of Patella : A Rare Case

Osteoblastoma of Patella : A Rare Case

A Rare Case of Rib Osteoblastoma: Imaging Features and Review of Literature

Pediatric sarcomas occurring in adults

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