Periorbital Granuloma Annulare

McFarland, Joseph P.

doi:10.1001/archderm.1982.01650150052024

Cited by 17 publications

(12 citation statements)

References 7 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…5 Unusual clinical variants of localized GA include a papular, umbilicated presentation, 12 as well as involvement of the eyelids, 13,14 penis, 15 mucosal surfaces, 16 periorbital area, 17 and face. 18,19 A follicular pustular form of localized GA has been reported.…”

Section: Etiologymentioning

confidence: 99%

Collagenolytic (necrobiotic) granulomas: part 1 – the ‘blue’ granulomas

Lynch

Barrett

2004

J Cutan Pathol

View full text Add to dashboard Cite

A collagenolytic or necrobiotic non-infectious granuloma is one in which a granulomatous infiltrate develops around a central area of altered collagen and elastic fibers. The altered fibers lose their distinct boundaries and exhibit new staining patterns, becoming either more basophilic or eosinophilic. Within the area of altered collagen, there may be deposition of acellular substances such as mucin (blue) or fibrin (red), or there may be neutrophils with nuclear dust (blue), eosinophils (red), or flame figures (red). These color distinctions can be used as a simple algorithm for the diagnosis of collagenolytic granulomas, i.e. 'blue' granulomas vs. 'red' granulomas. Eight diagnoses are included within these two groupings, which are discussed in this two-part article. In this first part, the clinical presentation, pathogenesis, and histologic features of the 'blue' collagenolytic granulomas are discussed. These are the lesions of granuloma annulare, Wegener's granulomatosis, and rheumatoid vasculitis. In the subsequent half of this two-part series, the 'red' collagenolytic granulomas will be discussed; these are the lesions of necrobiosis lipoidica, necrobiotic xanthogranuloma, rheumatoid nodules, Churg-Strauss syndrome, and eosinophilic cellulitis (Well's syndrome).Lynch JM, Barrett TL. Collagenolytic (necrobiotic) granulomas: part 1 -the 'blue' granulomas.

show abstract

Section: Etiologymentioning

confidence: 99%

Collagenolytic (necrobiotic) granulomas: part 1 – the ‘blue’ granulomas

Lynch

Barrett

2004

J Cutan Pathol

View full text Add to dashboard Cite

show abstract

“…12 In the ophthalmic literature, clinically and pathologically, identical ocular lesions have been independently reported as pseudorheumatoid nodules 3,7-9,13 and granuloma annulare. [4][5][6] To describe these identical ocular lesions and to unify general pathological, dermatological and ophthalmic description, Burnstine et al proposed the term granuloma annulare-nodular type. 2 Granuloma annulare may occur as an isolated process, but a clear association has been found between granuloma annulare and insulin-dependent diabetes.…”

Section: Commentmentioning

confidence: 99%

“…6 For an anticoagulated patient on warfarin, this allows time for the warfarin to be stopped or the patient to be heparinised prior to surgery.Our patient had systemic risk factors associated with suprachoroidal haemorrhage, namely advanced age and atherosclerosis. In this case, we hypothesize that the macular disciform lesion bled and the haemorrhage extended extensively due to the increased clotting time induced by the warfarin.…”

mentioning

confidence: 99%

“…6 For an anticoagulated patient on warfarin, this allows time for the warfarin to be stopped or the patient to be heparinised prior to surgery.…”

mentioning

confidence: 99%

“…1 Granuloma annulare involving the peri-ocular dermis has been well documented. [2][3][4][5][6][7] However orbital granuloma annulare is very rare. 2,4,8,9 Although an association between dermal granuloma annulare and diabetes has been documented, orbital granuloma annulare in insulin-dependent diabetes had not been reported previously.…”

mentioning

confidence: 99%

See 2 more Smart Citations

Orbital nodular-granuloma annulare in a juvenile diabetic

Ramaesh

Bhagat

Wharton

et al. 2002

Eye

View full text Add to dashboard Cite

670Eye usually deferred for 1-2 weeks, although the timing is a controversial issue. 6 For an anticoagulated patient on warfarin, this allows time for the warfarin to be stopped or the patient to be heparinised prior to surgery.Our patient had systemic risk factors associated with suprachoroidal haemorrhage, namely advanced age and atherosclerosis. In this case, we hypothesize that the macular disciform lesion bled and the haemorrhage extended extensively due to the increased clotting time induced by the warfarin.This case illustrates the risk of visual loss due to ocular haemorrhage in patients on anticoagulant therapy. Medical staff should be aware of the potentially devastating visual consequences of anticoagulation above the normal therapeutic range. References

show abstract