Perioperative ketamine for acute postoperative pain

The Use of Intravenous Infusion or Single Dose of Low-Dose Ketamine for Postoperative Analgesia: A Review of the Current Literature

“…Concerning safety, we reported results similar to previous reviews on ketamine [12–14,20]. The administration of ketamine was not associated with serious side effects or a significant increase in the likelihood of adverse events among the 2,482 patients we reviewed (1,403 of whom received ketamine).…”

The Use of Intravenous Infusion or Single Dose of Low-Dose Ketamine for Postoperative Analgesia: A Review of the Current Literature

“…Concerning safety, we reported results similar to previous reviews on ketamine [12–14,20]. The administration of ketamine was not associated with serious side effects or a significant increase in the likelihood of adverse events among the 2,482 patients we reviewed (1,403 of whom received ketamine).…”

Comparison between the Combination of Gabapentin, Ketamine, Lornoxicam, and Local Ropivacaine and Each of these Drugs Alone for Pain after Laparoscopic Cholecystectomy: A Randomized Trial

“…In the present study, ketamine alone did not to provide satisfactory analgesia, potentially reflecting the administration of a low dose of ketamine (a single dose of 0.3 mg/kg before incision), despite the fact that doses greater than 30 mg/24 hours have not proven to be more effective in treating postoperative pain . The administration of local ropivacaine reduced morphine consumption only during the first 6 postoperative hours.…”

Low-Dose Ketamine Infusion for Emergency Department Patients with Severe Pain

“…Ketamine administered as a single 15 mg IV bolus produces rapid and profound analgesia in an average sized adult, but the effect is short lived. This is distinct from the more gradual onset and sustained analgesic effect of opioids . We found that the majority of subjects in our study experienced significant pain relief at 10 minutes, reflecting the predictably strong analgesic effect of a 15 mg ketamine bolus.…”

The Use of Intravenous Infusion or Single Dose of Low-Dose Ketamine for Postoperative Analgesia: A Review of the Current Literature

“…Concerning safety, we reported results similar to previous reviews on ketamine [12–14,20]. The administration of ketamine was not associated with serious side effects or a significant increase in the likelihood of adverse events among the 2,482 patients we reviewed (1,403 of whom received ketamine).…”

Comparison between the Combination of Gabapentin, Ketamine, Lornoxicam, and Local Ropivacaine and Each of these Drugs Alone for Pain after Laparoscopic Cholecystectomy: A Randomized Trial

“…In the present study, ketamine alone did not to provide satisfactory analgesia, potentially reflecting the administration of a low dose of ketamine (a single dose of 0.3 mg/kg before incision), despite the fact that doses greater than 30 mg/24 hours have not proven to be more effective in treating postoperative pain . The administration of local ropivacaine reduced morphine consumption only during the first 6 postoperative hours.…”

Low-Dose Ketamine Infusion for Emergency Department Patients with Severe Pain

“…Ketamine administered as a single 15 mg IV bolus produces rapid and profound analgesia in an average sized adult, but the effect is short lived. This is distinct from the more gradual onset and sustained analgesic effect of opioids . We found that the majority of subjects in our study experienced significant pain relief at 10 minutes, reflecting the predictably strong analgesic effect of a 15 mg ketamine bolus.…”

The Use of Intravenous Infusion or Single Dose of Low-Dose Ketamine for Postoperative Analgesia: A Review of the Current Literature

“…Concerning safety, we reported results similar to previous reviews on ketamine [12–14,20]. The administration of ketamine was not associated with serious side effects or a significant increase in the likelihood of adverse events among the 2,482 patients we reviewed (1,403 of whom received ketamine).…”

Comparison between the Combination of Gabapentin, Ketamine, Lornoxicam, and Local Ropivacaine and Each of these Drugs Alone for Pain after Laparoscopic Cholecystectomy: A Randomized Trial

“…In the present study, ketamine alone did not to provide satisfactory analgesia, potentially reflecting the administration of a low dose of ketamine (a single dose of 0.3 mg/kg before incision), despite the fact that doses greater than 30 mg/24 hours have not proven to be more effective in treating postoperative pain . The administration of local ropivacaine reduced morphine consumption only during the first 6 postoperative hours.…”

Low-Dose Ketamine Infusion for Emergency Department Patients with Severe Pain

“…Ketamine administered as a single 15 mg IV bolus produces rapid and profound analgesia in an average sized adult, but the effect is short lived. This is distinct from the more gradual onset and sustained analgesic effect of opioids . We found that the majority of subjects in our study experienced significant pain relief at 10 minutes, reflecting the predictably strong analgesic effect of a 15 mg ketamine bolus.…”