Performance of the Pediatric Index of Mortality 2 in a pediatric intensive care unit

Netto, Antônio Lima; Muniz, Virginia Maria; Zandonade, Eliana; Maciel, Ethel Leonor Nóia; Bortolozzo, Rodrigo Nichio; Costa, Nélio Ferreira; Limongi, Rosane da Silva de Araujo

doi:10.5935/0103-507x.20140007

Cited by 15 publications

(10 citation statements)

References 28 publications

(36 reference statements)

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“…Majority of cases were male (60%) in other study also with no significant difference in mortality. 22 Mean duration of PICU stay was 6.85 days which is similar to that of study done in Japan 24 6.7 days and Africa 29 6 days. Major causes for PICU admission were sepsis/septic shock 33.9% and respiratory diseases 25.2%.…”

Section: Discussionsupporting

confidence: 82%

“…Mean age of patients were comparable with other studies. Mean age was 35 months in our study, it was 42 months 22 , 45 months 23 and 44 months 24 in other studies.…”

Section: Discussionsupporting

confidence: 56%

“…14 Our mortality is also similar to mortality observed in other developing countries like India 28%. 28 Lower mortality in unit like 2.6% in Argentina and Japan, 23,24 5.5% in Barbados, 25 14.23% in Brazil, 22 15% in Iran 26 are also reported. Some unit reported mortality as high as 46.2% in India, 27 which is due to late referral to their unit.…”

Section: Discussionmentioning

confidence: 84%

“…Similar discriminatory performance with area under curve of 0.80 to 0.90 was reported in studies done in Pakistan, 13 Barbados, 25 India, 27 and South Africa. 30 Just acceptable discrimination with area under ROC curve of 0.7-0.8 was reported in study from Brazil, 22 Iran, 26 India, 28 Africa, 29 and Egypt. 31 Very good discrimination with area under ROC curve of >0.9 was reported in study from Argentina, 23 Japan, 24 and Croatia.…”

Section: Discussionmentioning

confidence: 85%

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Performance of Pediatric Index of Mortality-2 in a Pediatric Intensive Care Unit of a Tertiary Care Hospital of Nepal

2019

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Various scoring system have been developed and are becoming essential part of Pediatric and other critical care units. The Pediatric department wants to introduce Pediatric Index of Mortality-2 (PIM 2) as a predictive scoring system in Pediatric critical care unit of Nepal Medical College Teaching Hospital (NMCTH). This was a prospective cohort study done in Pediatric Intensive Care Unit (PICU) of NMCTH. Study was done from August 2017 to December 2018. All cases admitted in ICU were taken consecutively from term newborn to 14 yrs of age. PIM 2 scoring system was done in all patients. PIM 2 performed well in terms of discrimination with area under curve for PIM 2 scor e was 0.809 with 95% Confidence Interval of 0.0709 to 0.910 and Standard Error of 0.051. Good calibration was observed across deciles of risk as measured by Hosmer-Lemeshow goodness of fit test with P value of 0.163, chi-square value of 11.752 (8). Mortality observed in our PICU was 28.4% with standardized mortality ratio of 1. PIM 2 scoring system performed well in our PICU.

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Section: Discussionsupporting

confidence: 82%

“…Mean age of patients were comparable with other studies. Mean age was 35 months in our study, it was 42 months 22 , 45 months 23 and 44 months 24 in other studies.…”

Section: Discussionsupporting

confidence: 56%

Section: Discussionmentioning

confidence: 84%

Section: Discussionmentioning

confidence: 85%

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Performance of Pediatric Index of Mortality-2 in a Pediatric Intensive Care Unit of a Tertiary Care Hospital of Nepal

2019

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“…From the medical records, we gathered demographic data, clinical data and laboratory findings suggesting small molecule disorders. Other data that were recorded by the residents were the Paediatric Index of Mortality 2 (PIM2) at admission, a scoring system for rating the severity of medical illness for children encompassing 10 physiological variables collected from the time of first physical contact between the patient and the PICU team up until 1 hour after physical PICU admission (4,5), and paediatric logistic organ dysfunction (PELOD) score on day 2 in the PICU, a scoring system covering of physical and laboratory variables representing 6 organ systems: nervous, cardiovascular, renal, respiratory, haematologic and hepatic systems. Each variable is assigned points (0, 1, 10, or 20) based on the level of severity, each organ dysfunction receives points for the variable associated with the highest number of points (6).…”

Section: Introductionmentioning

confidence: 99%

A retrospective study of small molecule disorder types of metabolism in paediatric patients in intensive care

El-Nawawy

Dawood

Omar

2018

East Mediterr Health J

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No statistics on small molecule disorders of IEM are available in Egypt. The aim of this retrospective study was to analyse the epidemiological and clinical data, final diagnoses and clinical outcomes of patients admitted to the paediatric intensive care unit (PICU) at Alexandria University Children's Hospital with a suspected or confirmed diagnosis of small molecule disorders. Methods In this 5-year retrospective study, we collected medical records of all patients admitted to the PICU at El-Shatby Children's Hospital, a tertiary care teaching hospital affiliated to Alexandria University (serving 4 governorates comprising 14 million people), from 1 January 2010 to 31 December 2014 (n = 1417). Ages ranged from 1 month to 6 years. The policy of our hospital is that all cases of small molecule disorders presented at the emergency room are admitted to PICU. Inclusion criteria were: confirmed diagnosis of small molecule disorders and suspected diagnosis of small molecule disorders at the time of PICU admission or during PICU stay, with no subsequent confirmation of diagnosis (according to PICU protocol). The exclusion criterion was previous diagnosis of small molecule disorders in patients admitted to the PICU during the study period. Out of 1417 PICU admissions, 34 patients (2.4%) had a suspected or confirmed small molecule disorder.

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Hypophosphatemia in critically ill pediatric patients receiving enteral and oral nutrition

Springer

Hortêncio

Melro

et al. 2021

J Parenter Enteral Nutr

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Background: Hypophosphatemia(HP) is related to several comorbidities in pediatric intensive care units (PICUs). This study aimed to evaluate the incidence of HP in severely ill pediatric patients receiving oral and/or enteral nutrition. The secondary objectives were to investigate the association between HP and the inflammatory state, PICU length of stay, severity, mortality, nutrition status, and protein, energy, calcium, vitamin D, and phosphate intake. Methods:A prospective, observational cohort study was conducted in a PICU of a quaternary hospital. Participants aged between 28 days and 14 years were included.Anthropometric and laboratory assessments were performed ≤72 h after PICU admission and repeated after 7 days for three consecutive times. Energy, protein, calcium, phosphate, and vitamin D intake per day of hospitalization were recorded individually.The Pediatric Index of Mortality 2 (PIM2) was used to determine each patient's severity score.Results: A total of 103 participants were included in the study. Hypophosphatemic events ranged from 27.2% to 37.5% among the assessments. HP was associated with high C-reactive protein levels (P = .012) and lower energy adequacy (P = .037). Serum phosphorus was inversely correlated (weak correlation) with PIM2 (P = .017). Conclusion:HP is common in critically ill pediatric patients, even when they are not receiving parenteral nutrition. It is necessary to monitor serum phosphorus levels and consider the possibility of early replacement, especially in patients showing high levels of inflammation. In addition to inflammation itself, low energy intake and illness severity were related to HP.

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Performance of the Pediatric Index of Mortality 2 in a pediatric intensive care unit

Cited by 15 publications

References 28 publications

Performance of Pediatric Index of Mortality-2 in a Pediatric Intensive Care Unit of a Tertiary Care Hospital of Nepal

Performance of Pediatric Index of Mortality-2 in a Pediatric Intensive Care Unit of a Tertiary Care Hospital of Nepal

A retrospective study of small molecule disorder types of metabolism in paediatric patients in intensive care

Hypophosphatemia in critically ill pediatric patients receiving enteral and oral nutrition

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