Percutaneous umbilical blood sampling: current trends and outcomes

Bigelow, Catherine A.; Cinelli, Christina; Little, Sarah E; Benson, Carol B.; Frates, Mary C.; Wilkins‐Haug, Louise

doi:10.1016/j.ejogrb.2016.02.038

Cited by 13 publications

(9 citation statements)

References 18 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This revolutionary technique, which directly collects fetal data via blood sampling, provides clinical information for a variety of fetal diseases . Suspected severe fetal anemia remains the most frequent indication for PUBS worldwide, accounting for 40% to 70% of cases . In our study, the investigation of fetal anemia was also the primary indication for PUBS, being reported in up to 70% of cases.…”

Section: Discussionmentioning

confidence: 63%

See 1 more Smart Citation

Current status of percutaneous umbilical cord blood sampling in Japan

Sasahara

Ishii

Fujikawa

et al. 2019

J of Obstet and Gynaecol

View full text Add to dashboard Cite

Aim: The aim of the survey is to investigate current practice and complications of percutaneous umbilical cord blood sampling (PUBS) in Japan. Methods: In this retrospective survey, data including perioperative information, indications, details of the procedure and procedure-related complications were collected for patients who underwent PUBS between 2012 and 2016 in Japanese perinatal care centers. Results: One hundred and fifty-three patients underwent PUBS and a total of 223 procedures were analyzed in this study. Fetal anemia was the most common indication for PUBS, representing greater than 70% of all cases. Anemia specific to monochorionic twins, such as acute feto-fetal hemorrhage subsequent to single intrauterine fetal death (IUFD) and twin anemia-polycythemia sequence, were the leading causes of suspected fetal anemia. Maternal anesthetics were given during the procedure in 70% of cases. The PTC needle (Hakko, Japan) was most commonly used in the procedure. The most frequent complication was bleeding from the umbilical cord puncture site; however, it did not require immediate delivery during or after the procedure in any case. IUFD occurred in 11 (4.9%) procedures, 7 of which appeared to be related to the underlying fetal disease. The overall completion rate of the procedure was 97%. Conclusion: Percutaneous umbilical cord blood sampling was most commonly performed for the evaluation of fetal anemia, usually due to complications of monochorionic twins, followed by the measurement of fetal thyroid function. The safety and the completion rate of the procedure in Japan appear satisfactory.

show abstract

Section: Discussionmentioning

confidence: 63%

“…Furthermore, the rate of fetal anemia related to red‐cell alloimmune disorders is expected to decrease. Thus it is anticipated that parvovirus B19 infection might overtake red‐cell alloimmune disorders as one of the most common indications for PUBS …”

Section: Discussionmentioning

confidence: 99%

Current status of percutaneous umbilical cord blood sampling in Japan

Sasahara

Ishii

Fujikawa

et al. 2019

J of Obstet and Gynaecol

View full text Add to dashboard Cite

show abstract

“…Of the 896 articles identified through the search, 87 were assessed for their eligibility (Table S2) and 35 studies were eventually included in the systematic review (Figure and Table ). These 35 studies included 611 fetuses affected by PB19 infection based on serological or virological confirmation or presence of signs of fetal anemia, such as hydrops, on ultrasound in fetuses with infected mothers. The definition of fetal hydrops in each included study is reported in Table S3.…”

Section: Resultsmentioning

confidence: 99%

Outcome of fetuses with congenital parvovirus B19 infection: systematic review and meta‐analysis

Bascietto

Liberati

Murgano

et al. 2018

Ultrasound in Obstet & Gyne

View full text Add to dashboard Cite

show abstract

“…Higher procedure-related complications may occur in high-risk pregnancies, for example in association with intrauterine growth restriction, non-immune fetal hydrops, chromosomal abnormalities. It is reported in 3.2 -10.2 % (1,2,5,6). We have to consider some complication as: bleeding from the injection site (20-30 %), severe fetal bradycardia (5-10 %) in certain cases requiring emergency delivery (4), development of chorioamnionitis, paraumbilical hematoma and vertical transmission of human immunodefi ciency virus or hepatitis transmission (1,3,4).…”

Section: Discussionmentioning

confidence: 95%

The value of cordocentesis in current management of intrauterine patient

Kunochova¹,

Papcun²,

Križko³

et al. 2019

BLL

View full text Add to dashboard Cite

OBJECTIVES: Analyzing the clinical group to evaluate current indications for cordocenteses, their complications and data obtained in further pregnancy management. METHODS: Retrospective analysis evaluated 92 cordocenteses (diagnostic and therapeutic) performed during the period of 2007-2018. These were performed between 17 and 36 weeks of gestation under ultrasound guidance by a specialist at 2nd Department of Gynecology and Obstetrics, Faculty of Medicine, Comenius University. RESULTS: Out of 92 procedures, 78 were diagnostic and 14 were therapeutic. The diagnostic cordocentesis was successful in 97.4 % and intrauterine therapy was successful in 85.7 %. There were 2 (2.56 %) diagnostic cordocenteses complicated by fetal demise and 2 (14 %) intrauterine demises in therapeutic cordocentesis. The pathological karyotype was detected in 14.5 %. Aneuploidia was present in 4 cases (44.4 %), mosaicism in 4 cases (44.4 %) and triploidia in one case (11.1 %). CONCLUSION: Despite of novel molecular genetic technique cordocentesis still plays unreplaceable role in current prenatal diagnosis and treatment. The risk of complications of cordocentesis increases depending on the severity of fetal pathology in pathologic pregnancies. In some situations it can be used as a useful tool for original fetal diagnosis and therapy (Tab. 3, Ref. 20). Text in PDF www.elis.sk.

show abstract

Percutaneous umbilical blood sampling: current trends and outcomes

Cited by 13 publications

References 18 publications

Current status of percutaneous umbilical cord blood sampling in Japan

Current status of percutaneous umbilical cord blood sampling in Japan

Outcome of fetuses with congenital parvovirus B19 infection: systematic review and meta‐analysis

The value of cordocentesis in current management of intrauterine patient

Contact Info

Product

Resources

About