Percentage of Fellow Eyes That Develop Full-Thickness Macular Hole in Patients With Unilateral Macular Hole

Risk Factors for Progression of Vitreomacular Traction to Macular Hole

“…In a subgroup analysis, we found that an FTMH in the fellow eye increased the likelihood that VMT in the study eye would progress to FTMH, with 24.0% of eyes with an FTMH in the fellow eye progressing to an FTMH over the study period. Previous studies have estimated that up to 25% of patients with a unilateral MH eventually develop bilateral involvement 22,37 ; however, we did not find a correlation between an LMH in the fellow eye and progression of the study eye to an LMH or to FTMH. A previous study of 35 patients over 4.6 years similarly suggested that the presence of an LMH in 1 eye does not significantly increase the risk for developing an LMH in the fellow eye.…”

Comparison of retinal vascular arcade trajectory between eyes with an idiopathic macular hole and the healthy fellow eye

“…Involving the fellow eye as control could be a power of the present study because it removes most of the confounding factors such as age, sex, and also most ocular biometric features, which are typically similar in fellow eyes. However, since the fellow eyes of IMHs are at greater risk of developing macular holes, [15] the ndings of this study should be con rmed by future studies with larger sample sizes that include normal patients as well. Finally, we used Photoshop CS6 interface to calculate retinal distances; and therefore, the measured distances (in micrometers) are not exactly the actual values (and are somehow magni ed).…”

Macular Structure Characteristics in Unilateral Idiopathic Full-Thickness Macular Hole and the Healthy Fellow Eyes

“…It is well known that patients with unilateral FTMH also have an increased risk of developing FTMH in their fellow eyes. [16][17][18] Previous studies also demonstrated that symmetric foveal configuration exists in both eyes. 19,20 Since the macular structure changes after the formation of FTMH, the macular structure of the fellow eyes of patients with unilateral FTMH should also provide some information regarding the vitreoretinal interface and macular structure, that may result in the formation of FTMH.…”