“…Multimorbidity, "the most common chronic condition experienced by adults", places significant demands on individuals, clinicians and the health system (25). Individuals must navigate an illness trajectory complicated by processes of adaption and re-adaption linked to each subsequent diagnosis (135,182,194 Research investigating the experience of managing multiple chronic conditions has grown in prominence in recent years, as an increasing number of largely qualitative studies have examined the challenges people face (133,135,(195)(196)(197)(198) Treatment burden arises from the need to learn about treatments, attend medical appointments, undergo tests or examinations, and adhere to complex medication and self-care regimens (95,199,201,202). For those managing multiple chronic conditions these demands are amplified in the face of unwanted complications and complexity (73,95,202,203).…”