PERBANDINGAN AKTIVITAS ANTIOKSIDAN BEBERAPA EKSTRAK DAUN COCOR BEBEK (Kalanchoe pinnata) DENGAN MENGGUNAKAN METODE DPPH

Sylvia, Diana; Fatimah, Fatimah; Pratiwi, Dina

doi:10.52434/jfb.v11i1.718

Cited by 5 publications

(5 citation statements)

References 7 publications

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“…Meanwhile, at concentrations of 7.5% and 15% of cocor bebek (Kalanchoe pinnata) leaf ethanol extract given to Salmonella typhi bacteria, there was an inhibitory response even though it was included in the category of no inhibition zone based on Greenwood classification. It is also in line with Sylvia [25] which showed that the 30% concentration of cocor bebek leaves ethanol extract was classified as a weak inhibitory response, while concentrations of 15% and 7.5% were categorized as having no inhibitory response.…”

Section: Discussionsupporting

confidence: 76%

Antibacterial test of ethanol extract of "Cocor-Bebek" leaves (Kalanchoe pinnata) against the growth of Staphylococcus aureus and Salmonella typhi

Sudayasa¹,

Dewi²,

Ariasnitra³

et al. 2022

GSC Biol. and Pharm. Sci.

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This study aims to determine the antibacterial effect of the Ethanol Extract of Cocor bebek leaves (Kalanchoe pinnata) on the growth of Staphylococcus aureus and Salmonella typhi. The study is a true experimental, using a posttest only control group design with the independent variable being the extract of cocor bebek leaves (Kalanchoe pinnata). This study found that extracts of cocor bebek leaves (Kalanchoe pinnata) with a concentration of 7.5% and 15% had no inhibitory power, while at concentrations of 30% and 60% had weak inhibitory power as the minimum inhibitory power, and a concentration of 100% had inhibitory power, and strong on the growth of Staphylococcus aureus bacteria. Meanwhile for the growth of Salmonella typhi, a concentration of 7.5% from 3 repetitions had an average inhibition zone of 1.2 mm. for a concentration of 15% has an average inhibition zone diameter of 3 repetitions of 2.2 mm. concentration of 30% from 3 rolls has an average inhibition zone of 12.6 mm. for a concentration of 60% has an average inhibition zone of 3 repetitions of 19.8mm. There is antibacterial activity of ethanolic extract of cocor bebek leaf (Kalanchoe pinnata) against the growth of Staphylococcus aureus and Salmonella typhi.

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Section: Discussionsupporting

confidence: 76%

Antibacterial test of ethanol extract of "Cocor-Bebek" leaves (Kalanchoe pinnata) against the growth of Staphylococcus aureus and Salmonella typhi

Sudayasa¹,

Dewi²,

Ariasnitra³

et al. 2022

GSC Biol. and Pharm. Sci.

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“…Copyright © 2024, Universitas Sebelas Maret, ISSN 1412-4092, e ISSN 2443-4183 menunjukkan bahwa daun L. firma terekstraksi dengan sangat baik dan mengandung lebih banyak senyawa metabolit sekunder dibandingkan ekstrak dari akar dan batang. Pelarut etanol digunakan karena merupakan pelarut universal yang dapat melarutkan hampir semua senyawa organik yang ada pada suatu sampel, baik senyawa polar maupun senyawa non polar dan relatif aman dibandingkan metanol (Noviyanti, 2016). Perbandingan rendemen ekstrak etanol daun L. firma dengan ekstrak etanol dari spesies Litsea lainnya menunjukkan bahwa rendemen ekstrak etanol daun L. firma relatif lebih besar daripada ekstrak etanol dari daun L. elliptica (10,4% w/w) (Mariani et al, 2021), L. monopetala (4% w/w) (Hasan et al, 2014), dan L. cubeba (20% w/w) (Wong et al, 2022).…”

Section: Hasil Dan Pembahasanunclassified

Profil Kandungan Kimia, Fenolik Total, dan Aktivitas Antioksidan Ekstrak Etanol Tumbuhan Litsea firma (Blume) Hook F

Putri,

Muharini,

Lestari

et al. 2024

ALCHEMY J. Pen. Kim

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Litsea firma (Blume) Hook f atau medang piawas merupakan salah satu tumbuhan tingkat tinggi yang dijumpai di Kabupaten Melawi, Kalimantan Barat, Indonesia. Masyarakat setempat memanfaatkannya sebagai obat tradisional untuk menyembuhkan alergi kulit dan menghilangkan bau badan. Penelitian ini bertujuan untuk menentukan profil kandungan kimia, fenolik total, dan aktivitas antioksidan ekstrak akar, batang, dan daun Litsea firma. Analisis fitokimia dan kromatogram reversed phase-high performance liquid chromatography (RP-HPLC) menunjukkan bahwa komponen utama pada setiap ekstrak etanol adalah golongan senyawa fenolik dan cenderung bersifat polar. Kadar fenolik total ditentukan menggunakan metoda Folin-Ciocalteu. Hasil menunjukkan bahwa kadar fenolik total tertinggi adalah ekstrak etanol batang sebesar 90,85 mg GAE/g ekstrak, diikuti ekstrak akar (70,29 mg GAE/g ekstrak) dan daun (51,52 mg GAE/g ekstrak). Penentuan aktivitas antioksidan dilakukan menggunakan 2,2-Diphenyl-1-picrylhydrazyl (DPPH) dengan asam askorbat sebagai kontrol positif. Ekstrak akar, batang, dan daun menunjukkan aktivitas antioksidan moderat dengan IC50 secara berurutan sebesar 134,45 ppm, 112,21 ppm, dan 157,94 ppm,. Dengan demikian, ekstrak batang merupakan sumber senyawa fenolik dan antioksidan yang lebih baik dibandingkan bagian lain tumbuhan L. firma (Blume) Hook f. Characterization of Chemical Composition, Phenolic Content, and Antioxidant Activity of Ethanol Extract from Litsea firma (Blume) Hook F Plants. Litsea firma (Blume) Hook f is one of the higher plants distributed widely in Sungai Pinang Village, Melawi Regency, West Kalimantan, Indonesia. Local people use some parts of the plant as a traditional medicine to cure skin allergies and eliminate body odor. This study aimed to analyze the chemistry profile, measure the phenolic content, and determine the antioxidant activity of Litsea firma roots, stems, and leaf extracts. Phytochemical and reversed phase-high performance liquid chromatography (RV-HPLC) chromatogram analysis on each ethanolic extract showed that each extract possessed a similar phytochemical profile of polar phenolic compounds as major compounds. The Folin-Ciocalteu method was used to determine the total phenolic content using gallic acid as a standard. The results showed that the total phenolic content in the roots, stems, and leaves extract was 70.29, 90.85, and 51.52 mg GAE/g extract, respectively., where phenolic content in the stems was the highest. Antioxidant activity was evaluated using 2,2-Diphenyl-1-picrylhydrazyl (DPPH) with ascorbic acid as a reference standard. The extracts of the roots, stems, and leaves showed moderate antioxidant activity with IC50 values of 134.45 ppm, 112.21 ppm, and 157.94 ppm, respectively. Thus, stem extract Litsea firma Blume has a better antioxidant and phenolic resource from this species.

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“…Pemeriksaan ekstrak kental meliputi organoleptik (warna, bau, bentuk), uji ketercampuran dengan air dan etanol 96%, bobot jenis menggunakan piknometer, pH dengan menggunakan pH meter, dan identifikasi fenol menggunakan pereaksi FeCl3 1% (Diana, et al, 2020).…”

Section: Sosor Bebekunclassified

Formulasi Gel Ekstrak Daun Sosor Bebek (Kalanchoe pinnata (Lam.) Per.) dengan Kombinasi Carbophol 980 dan Cremophor RH 40

Kartiningsih¹,

Damayanti²,

Budiati

2023

JPS

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Daun sosor bebek (Kalanchoe pinnata P.) merupakan tanaman obat yang diketahui memiliki aktivitas antiseptik. Tujuan dari penelitian ini untuk melihat pengaruh konsentrasi Carbophol 980 dan Cremophor RH 40 terhadap mutu fisik dan pH sediaan gel ekstrak kental daun sosor bebek yang dianalisa dengan metode ANOVA satu arah. Daun sosor bebek diekstrasi dengan metode maserasi menggunakan etanol 96%, kemudian diformulasikan menjadi sediaan gel dengan kombinasi Carbophol 980 sebagai gelling agent dan Cremophor RH 40 sebagai wetting agent. Sediaan gel dibuat 8 formula dengan variasi konsentrasi Carbophol 980 0

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PERBANDINGAN AKTIVITAS ANTIOKSIDAN BEBERAPA EKSTRAK DAUN COCOR BEBEK (Kalanchoe pinnata) DENGAN MENGGUNAKAN METODE DPPH

Cited by 5 publications

References 7 publications

Antibacterial test of ethanol extract of "Cocor-Bebek" leaves (Kalanchoe pinnata) against the growth of Staphylococcus aureus and Salmonella typhi

Antibacterial test of ethanol extract of "Cocor-Bebek" leaves (Kalanchoe pinnata) against the growth of Staphylococcus aureus and Salmonella typhi

Profil Kandungan Kimia, Fenolik Total, dan Aktivitas Antioksidan Ekstrak Etanol Tumbuhan Litsea firma (Blume) Hook F

Formulasi Gel Ekstrak Daun Sosor Bebek (Kalanchoe pinnata (Lam.) Per.) dengan Kombinasi Carbophol 980 dan Cremophor RH 40

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