Peptidoglycan-inspired autonomous ultrafast self-healing bio-friendly elastomers for bio-integrated electronics

Abstract

<jats:title>Abstract</jats:title> <jats:p>Elastomers are essential for emerging stretchable electronics, which has become more and more important to bio-integrated devices. To ensure a high compliance to application environment, elastomers are expected to resist and even self-repair the mechanical damages, be friendly to human body. Herein, inspired by peptidoglycan, we designed the first room-temperature autonomous self-healing biodegradable and biocompatible elastomers, poly(sebacoyl 1,6-hexamethylenedicarbamate diglyceride) (PSeHCD) elastomers. The unique structure including alternating ester-urethane moieties and bionic hybrid crosslinking endowed PSeHCD elastomers superior properties: ultrafast self-healing, tunable biomimetic mechanical properties, facile reprocessability, as well as good biocompatibility and biodegradability. The potential of PSeHCD elastomers was demonstrated by super-fast self-healing stretchable conductor (21 s) and motion sensor (2 min). This work provides new design and synthetic principle of elastomers for the applications in bio-integrated electronics.</jats:p>

A Dynamically Hybrid Crosslinked Elastomer for Room‐Temperature Recyclable Flexible Electronic Devices

“…FPU was found to exhibit rapid self‐healing of scratches within 120 s at room temperature owing to the extensive distribution of hydrogen bonds in the molecular chain. [ 12 ] The mechanical properties and self‐healing efficiencies of the FPU were determined via tensile testing of the original samples and those self‐healed after 6 h of storage at different temperatures (Figure 2b,c). At room temperature (25 °C), FPU is observed to recover more than 50% of its original tensile strength within 6 h. The FPU exhibits a comparatively higher repair performance upon heating at a moderate temperature (60 °C), with the tensile strength recovering to more than 80% owing to activation of disulfide metathesis.…”

A Review: Optimization for Poly(glycerol sebacate) and Fabrication Techniques for Its Centered Scaffolds

“…There are also significant needs for biointegrated electronics that can overcome mechanical failure and be free of side effects to human tissues. [ 38 ] Zhang et al. approached this issue by synthesizing a peptidoglycan‐inspired polymer poly(sebacoyl 1,6‐hexamethylenedicarbamate diglyceride) (PSeHCD) and fabricating PSeHCD‐60/liquid metal conductor and PSeHCD‐60/poly(3,4‐ethylenedioxythiophene):poly(styrenesulfonic acid) (PEDOT:PSS) sensor, which was superfast self‐healing, stretchable and bio‐friendly.…”

“…approached this issue by synthesizing a peptidoglycan‐inspired polymer poly(sebacoyl 1,6‐hexamethylenedicarbamate diglyceride) (PSeHCD) and fabricating PSeHCD‐60/liquid metal conductor and PSeHCD‐60/poly(3,4‐ethylenedioxythiophene):poly(styrenesulfonic acid) (PEDOT:PSS) sensor, which was superfast self‐healing, stretchable and bio‐friendly. [ 38 ]…”

Supertough spontaneously self-healing polymer based on septuple dynamic bonds integrated in one chemical group

“…In 2008, Cordier and coworkers [1] pioneered the synthesis of self-healing polymers based on hydrogen bonds. Thereafter, spontaneously self-healing polymers have been synthesized based on various noncovalent interactions such as hydrogen bonds [22][23][24][25], metal-ligand coordination [26,27], ionic interactions [28][29][30], host-guest interactions [31], and π-π stacking interactions [32]. Additionally, spontaneously selfhealing has been achieved in polymers comprising dynamic covalent bonds such as disulfide bonds [33][34][35], boronic ester bonds [36], and urea bonds [13].…”