Pentazocine addiction among sickle cell disease patients and perception of its use among health-care workers

Akinbami, Akinsegun; Ola, Bola; Uche, Ebele; Badiru, Mulikat; Olowoselu, Olusola; Suleiman, Aishatu Maude; Augustine, Benjamin

doi:10.4103/joah.joah_39_19

Cited by 3 publications

(1 citation statement)

References 17 publications

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“…A retrospective review of one emergency room practice shows that the time to initial analgesic administration was still longer significantly than what is recommended by pain management guidelines (15 minutes from time of entering the Emergency Department). [35] Health care workers have been shown to overestimate the prevalence of opioid misuse among SCD patients [36] True addiction on the other hand is usually opioid use not related to pain control and patient can exhibit behaviours including self-administration of opioids in increasing doses, stealing of prescription pads, visiting multiple physicians and so on. [2] [19] Another area that could pose a challenge for physicians is distinguishing between a vasoocclusive episode and opioid induced hyperalgesia which occurs in patients who have been on chronic opioid use.…”

Section: The Dilemma: True Addiction and Pseudo-addiction In Sickle C...mentioning

confidence: 99%

Management of Opioid Use Disorder in Sickle Cell Anaemia amidst Growing Menace in the General Population

Aboluwarin,

Ojuawo,

Akanbi

et al. 2023

OJPed

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Nigeria has a very high number of sickle cell disease (SCD) population with addition of 150,000 babies born annually with the disease. Early infant diagnosis and good care make many of these babies survive to adulthood. Severe pain requiring moderately strong or very strong analgesics is a common presentation of patients with Sickle Cell Anaemia. Paediatricians find ready usefulness of Opioids which are very useful for the painful episodes among these patients. Therefore, the chances of abuse and addiction to these medications become very high and constitute additional burden on the deficient manpower in the health sector. Opioid Use Disorder among Sickle Cell Disease patients has subtle presentation, so a high index of suspicion is required to make both the diagnosis and referral to treatment centres. In this review, the epidemiology, pain pathophysiology, behavioural and pharmacologic therapy have been re-examined.

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Section: The Dilemma: True Addiction and Pseudo-addiction In Sickle C...mentioning

confidence: 99%

Management of Opioid Use Disorder in Sickle Cell Anaemia amidst Growing Menace in the General Population

Aboluwarin,

Ojuawo,

Akanbi

et al. 2023

OJPed

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Psychoactive substance use disorders in an adult sickle cell disease population in Nigeria: prevalence and correlates

Uthman

James

Omoaregba

2021

Journal of Substance Use

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Prevalence and factors associated with opioid use disorder among adolescents with sickle cell disease in Mulago hospital, Uganda

Kwagala,

Munube,

Abbo

et al. 2024

Child Adolesc Psychiatry Ment Health

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Background Opioid use disorder (OUD) among adolescents with sickle cell disease (SCD) patients increases their risk of complications from sickle cell disease, such as infections, stroke, acute chest syndrome, sudden death, and organ failure. This negatively impacts families, communities, the national health system, and the economy. This study aimed to determine the prevalence and factors associated with opioid use disorder among adolescents with SCD at Mulago Hospital Uganda. Methods This study was carried out at the Sickle Cell Clinic of Mulago Hospital, the national referral hospital in Uganda. The study participants were adolescents aged 10 to 19 years. Following informed consent/ assent, a sociodemographic questionnaire, the WHO Alcohol, Smoking and Substance Involvement Screening Test - Young (ASSIST-Y), the Beck Depression Inventory-II (BDI II), and Generalized Anxiety Disorder − 7 (GAD-7) questionnaires were used to collect data. Data was entered in EpiInfo and analyzed in STATA 15. Results The prevalence of opioid use disorder was 5.3%. The significant risk factor was increasing depressive score AOR: 1.11(95% CI: 1.01–1.22, p = 0.035), while living with a family was protective against opioid use disorders AOR: 0.01; (95% CI: 0.0004, 0.27, p = 0.007). Conclusion There was a significant problem of OUD among adolescents with SCD. There is, therefore, needed to integrate screening of OUD and mental illnesses like depression among adolescents with SCD and to emphasize the importance of family support in their care.

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Pentazocine addiction among sickle cell disease patients and perception of its use among health-care workers

Cited by 3 publications

References 17 publications

Management of Opioid Use Disorder in Sickle Cell Anaemia amidst Growing Menace in the General Population

Management of Opioid Use Disorder in Sickle Cell Anaemia amidst Growing Menace in the General Population

Psychoactive substance use disorders in an adult sickle cell disease population in Nigeria: prevalence and correlates

Prevalence and factors associated with opioid use disorder among adolescents with sickle cell disease in Mulago hospital, Uganda

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