Penicillin-Resistant Streptococcus constellatus as a Cause of Endocarditis

Evaluation of a rapid system for species identification of alpha-hemolytic streptococci

“…Murray et al 7also point out that species identification is important because S. milleri (intermedius) may be associated with serious suppurative infections. Identification and susceptibility testing may be more important in the future because of the emergence of penicillin-resistant organisms (6). We have found that species identification of alphahemolytic streptococci isolated from cerebrospinal fluid is useful in distinguishing clinically significant isolates from those considered to be contaminants, such as S. mitis (unpublished data).…”

“…The development of rapid methods for species identification of alpha-hemolytic streptococci would be of great value in clinical microbiology. This not only would provide rapid results, but also would provide the clinician with more spe-cific information on which to base initial therapeutic decisions, especially in light of a recent report of a penicillin-resistant alpha-hemolytic streptococcus (6). Recently, a new 4-h system for the identification of streptococci became available (API 20S; Analytab Products [API], Plainview, N.Y.).…”

Evaluation of a rapid system for species identification of alpha-hemolytic streptococci

“…Murray et al 7also point out that species identification is important because S. milleri (intermedius) may be associated with serious suppurative infections. Identification and susceptibility testing may be more important in the future because of the emergence of penicillin-resistant organisms (6). We have found that species identification of alphahemolytic streptococci isolated from cerebrospinal fluid is useful in distinguishing clinically significant isolates from those considered to be contaminants, such as S. mitis (unpublished data).…”

“…The development of rapid methods for species identification of alpha-hemolytic streptococci would be of great value in clinical microbiology. This not only would provide rapid results, but also would provide the clinician with more spe-cific information on which to base initial therapeutic decisions, especially in light of a recent report of a penicillin-resistant alpha-hemolytic streptococcus (6). Recently, a new 4-h system for the identification of streptococci became available (API 20S; Analytab Products [API], Plainview, N.Y.).…”

Infective endocarditis due to a rare pathogen, Streptococcus constellatus, in a patient with gingivitis: A case report and review of the literature

“…Only 10 cases are reported in the literature [5][6][7][8][9][10][11][12][13][14]. It is reported that S. constellatus is not readily associated with the heart valves, which may explain why S. constellatus rarely causes IE [15,16].…”

“…However, 1 group of S. viridans, the S. milleri group, which includes S. constellatus, S. anginosus, and S. intermedius, rarely cause IE; among these, S. anginosus is predominant [4]. S. constellatus is a very rare pathogen of IE; there are only 10 case reports in the literature [5][6][7][8][9][10][11][12][13][14]. The clinical features of IE due to S. constellatus remain unclear.…”

Streptococcus constellatusand Prevotella bivia Penile Abscess

“…These organisms are usually sensitive to βlactam antibiotics, such as penicillin, ceftriaxone and ampicillin, doxycycline, erythromycin, vancomycin, and the aminoglycosides, and intermediately sensitive to clindamycin. Increased resistance to penicillin and clindamycin has been described [12,14,15]. S. constellatus causes superficial abscesses often isolated with anaerobic bacteria [16].…”

Evaluation of a rapid system for species identification of alpha-hemolytic streptococci

“…Murray et al 7also point out that species identification is important because S. milleri (intermedius) may be associated with serious suppurative infections. Identification and susceptibility testing may be more important in the future because of the emergence of penicillin-resistant organisms (6). We have found that species identification of alphahemolytic streptococci isolated from cerebrospinal fluid is useful in distinguishing clinically significant isolates from those considered to be contaminants, such as S. mitis (unpublished data).…”

“…The development of rapid methods for species identification of alpha-hemolytic streptococci would be of great value in clinical microbiology. This not only would provide rapid results, but also would provide the clinician with more spe-cific information on which to base initial therapeutic decisions, especially in light of a recent report of a penicillin-resistant alpha-hemolytic streptococcus (6). Recently, a new 4-h system for the identification of streptococci became available (API 20S; Analytab Products [API], Plainview, N.Y.).…”

Infective endocarditis due to a rare pathogen, Streptococcus constellatus, in a patient with gingivitis: A case report and review of the literature

“…Only 10 cases are reported in the literature [5][6][7][8][9][10][11][12][13][14]. It is reported that S. constellatus is not readily associated with the heart valves, which may explain why S. constellatus rarely causes IE [15,16].…”

“…However, 1 group of S. viridans, the S. milleri group, which includes S. constellatus, S. anginosus, and S. intermedius, rarely cause IE; among these, S. anginosus is predominant [4]. S. constellatus is a very rare pathogen of IE; there are only 10 case reports in the literature [5][6][7][8][9][10][11][12][13][14]. The clinical features of IE due to S. constellatus remain unclear.…”

Streptococcus constellatusand Prevotella bivia Penile Abscess

“…These organisms are usually sensitive to βlactam antibiotics, such as penicillin, ceftriaxone and ampicillin, doxycycline, erythromycin, vancomycin, and the aminoglycosides, and intermediately sensitive to clindamycin. Increased resistance to penicillin and clindamycin has been described [12,14,15]. S. constellatus causes superficial abscesses often isolated with anaerobic bacteria [16].…”

Evaluation of a rapid system for species identification of alpha-hemolytic streptococci

“…Murray et al 7also point out that species identification is important because S. milleri (intermedius) may be associated with serious suppurative infections. Identification and susceptibility testing may be more important in the future because of the emergence of penicillin-resistant organisms (6). We have found that species identification of alphahemolytic streptococci isolated from cerebrospinal fluid is useful in distinguishing clinically significant isolates from those considered to be contaminants, such as S. mitis (unpublished data).…”

“…The development of rapid methods for species identification of alpha-hemolytic streptococci would be of great value in clinical microbiology. This not only would provide rapid results, but also would provide the clinician with more spe-cific information on which to base initial therapeutic decisions, especially in light of a recent report of a penicillin-resistant alpha-hemolytic streptococcus (6). Recently, a new 4-h system for the identification of streptococci became available (API 20S; Analytab Products [API], Plainview, N.Y.).…”

Infective endocarditis due to a rare pathogen, Streptococcus constellatus, in a patient with gingivitis: A case report and review of the literature

“…Only 10 cases are reported in the literature [5][6][7][8][9][10][11][12][13][14]. It is reported that S. constellatus is not readily associated with the heart valves, which may explain why S. constellatus rarely causes IE [15,16].…”

“…However, 1 group of S. viridans, the S. milleri group, which includes S. constellatus, S. anginosus, and S. intermedius, rarely cause IE; among these, S. anginosus is predominant [4]. S. constellatus is a very rare pathogen of IE; there are only 10 case reports in the literature [5][6][7][8][9][10][11][12][13][14]. The clinical features of IE due to S. constellatus remain unclear.…”

Streptococcus constellatusand Prevotella bivia Penile Abscess

“…These organisms are usually sensitive to βlactam antibiotics, such as penicillin, ceftriaxone and ampicillin, doxycycline, erythromycin, vancomycin, and the aminoglycosides, and intermediately sensitive to clindamycin. Increased resistance to penicillin and clindamycin has been described [12,14,15]. S. constellatus causes superficial abscesses often isolated with anaerobic bacteria [16].…”