Penicillin in Iodized Oil for Instillation Into the Lungs

Abstract

(1) A suspension of calcium penicillin in 40 per cent. iodized oil produces a stable mixture which has been instilled in the lungs of 12 patients without adverse effect and has maintained penicillin in the lung for a minimum of 24 hours, after a single instillation. (2) The penicillin iodized oil has maintained its potency for 60 days at ice box, room and 37 degrees C. temperatures.

Current Comment

“…It does not discolor the skin, as does quinacrine, nor does it give the disagreeable gastro¬ intestinal symptoms which are sometimes seen with the administration of quinacrine. 3. The exploration of the 8-aminoquinolines.…”

“…They feel that the increased cost of such mixtures should not be made the basis of permitting a practice that is dangerous as well as unphysiologic. 3 Medical Service and its subcommittee. It is now not necessary for a physician veteran of any age to prove that his education was interrupted to become eligible ; more satisfactory arrangements for tuition payments for short courses are provided ; tuition and subsistence bene¬ fits will not be charged against the veteran's bonus, should one be voted later by Congress; and the sub¬ sistence benefits are increased.…”