PENGARUH INFUS RIMPANG TEMULAWAK (Curcuma xanthorrhiza) TERHADAP KADAR HEMOGLOBIN DAN JUMLAH ERITROSIT TIKUS PUTIH YANG DIBERI LARUTAN TIMBAL NITRAT [(PbNO3)2]

Abstract

The purpose of this experiment was to study the effect of turmeric (Curcuma xanthorrhiza) rhizome infuse to hemoglobin concentration and number of erythrocyte of (PbNO3)2 treated rats. Pb was presumed to be link at sulphyhydril groups that may caused an inhibition to several enzymatic process, such as d-ALAD and heme sintetase which is caused the inhibits of Hb synthesis and erythropoesis. Twenty female rats was used in this experiment. They were divided into five groups, i.e. (A) control (treated with 1 ml aquadest), (B) treated with 1/2 ml of 12 ppm lead solution and 1/2 ml aquadest, (C) treated with 1/2 ml of 12 ppm lead solution and 1/2 ml of 20 percent turmeric rhizome infuse, (D) treated with 1/2 ml of 50 ppm lead solution and 1/2 ml aquadest, (E) treated with 1/2 ml of 50 ppm lead solution and 1/2 ml of 20 percent turmeric rhizome infuse. The treatment was given orally every day (30 days) using a modified syringe. After 30 days of treatment, the blood sample were taken about 2 ml by heart puncture. The Hb concentration was determined using by Cyanmethemoglobin method and number of erythrocyte was counting on Haemocytometer Improved Neubauer. Data were analyzed by Anova and LSD test (a = 0.05). The results of this study shows that 20 percent of turmeric rhizome infuse statistically has a significant effect (P less than 0.05) to increasing of hemoglobin concentration but hasn’t significant to prevent the number of erythrocyte decreasing of [(PbNO3)2] treated.

Effect of Consuming Temulawak (Curcuma Xanthorrhiza Roxb.) Extract on Breast Milk Production in Postpartum Mothers

“…19 The results of this study are also in line with the previous studies, which indicated that there was a significant effect of temulawak extract on breast milk production and prolactin levels. 8,9…”

“…8 There was an influence of temulawak consumption by postpartum mother to the smoothness of milk production. 9 Curcuma xanthorhiza Roxb contains lipid elements and hormonal structures in which these active compounds play an active role in the milk production process as they exhibit the lactagagum effect. 10 In addition, it contains polyphenols, which also play a role in increasing prolactin levels.…”