Autoimmune Bullous Diseases 2018
DOI: 10.5772/intechopen.71712
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Pemphigus: Subtypes, Clinical Features, Diagnosis, and Treatment

Abstract: Pemphigus is a group of autoimmune blistering disorders associated with autoantibodies against the keratinocyte cell surface. Pemphigus has three major variants: pemphigus vulgaris (PV), pemphigus foliaceus (PF), and paraneoplastic pemphigus (PNP) which all have further subtypes. The variants of pemphigus are classified depending upon the clinical and histological features, immunofluorescence staining pattern, and autoantibody profile of the disease. The onset and course of pemphigus appear on the basis of int… Show more

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Cited by 7 publications
(7 citation statements)
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“…He also added epistaxis and hoarseness of voice while mucosal erosion present. 15 Trunk was the commonest site of cutaneous involvement and oral mucosa was the next common site. In PV patients 71% were mucocutaneous type and 29% was cutaneous type but no one found pure mucous type.…”
Section: Treatment Profilementioning
confidence: 99%
“…He also added epistaxis and hoarseness of voice while mucosal erosion present. 15 Trunk was the commonest site of cutaneous involvement and oral mucosa was the next common site. In PV patients 71% were mucocutaneous type and 29% was cutaneous type but no one found pure mucous type.…”
Section: Treatment Profilementioning
confidence: 99%
“…4 Pencetus PV berasal dari berbagai faktor seperti obat-obatan (kaptopril, penisilamin), infeksi (virus herpes simpleks, virus Epstein-Barr, dan lain-lain), pestisida, radiasi ultraviolet, luka bakar, stres, dan makanan yang mengandung allium, fenol, tiol, atau urushiol. 10 Secara klinis, lesi kulit pada PV jarang dirasa gatal, lebih sering terasa nyeri. Lesi awal PV adalah bula kendur di permukaan kulit mana saja.…”
Section: Pemfigus Vulgaris �Pv�unclassified
“…The other intraepidermal immunobllous disorders are pemphigus foliaceus (PF), paraneoplastic pemphigus, intercellular immunoglobulin A (IgA) pemphigus, and pemphigus erythematous (PE). [5][6][7][8] The disease can be life-threatening in 5-10% of cases. An accurate diagnosis of disease requires a correlation of clinical findings and microscopy with findings on direct immunofluorescence (DIF).…”
Section: Introductionmentioning
confidence: 99%